課程名稱 |
分子演化: 理論與實作![](images/cancel.gif) Molecular Evolution: Principles and Practice |
開課學期 |
106-2 |
授課對象 |
生命科學所 |
授課教師 |
丁照棣 |
課號 |
EEB5087 |
課程識別碼 |
B44 U1990 |
班次 |
01 |
學分 |
3.0 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期一3,4,5(10:20~13:10) |
上課地點 |
生科419 |
備註 |
與王弘毅、胡哲明、李承叡 總人數上限:40人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1062MolEvol |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
[Lectures]
This course is to introduce the fundamentals and methodology on research of molecular evolution. We will introduce the evolutionary changes and patterns of sequences, methods for phylogenetic analyses, and inferring sites under positive selection. Topics on recent advances of molecular evolution studies will be offered at the end, on phylogenomics, horizontal gene transfer, and genome evolution. Students are highly recommended to take evolution, genetics or equivalent subjects before taking this course. Laboratory practice will be offered for students to be familiar with data retrieving, analyses and interpretation. Homework assignments will be distributed weekly, which require substantial extra work time.
[Laboratory Practice]
We will have computers available in class, but you are welcome to bring your own laptop computer. In the later case, you should download the corresponding software before the class. Date sets will be provided for the homework assignments but you are welcome to use your own data for the final presentation project.
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課程目標 |
In combination with the computer laboratory practice, we aim to help our students to understand the evolutionary processes at the molecular level. |
課程要求 |
Biology; Evolutionary Biology; Genetics or equivalent preferred. |
預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
Molecular Evolution by Li W.-H. (Sinauer Associates, 1997)
Molecular Evolution: A Phylogenetic Approach by Roderick Page, D.M. and Holmes, E. C. (1998, Wiley-Blackwell)
Fundamentals of Molecular Evolution By Graur, D. and Li, W.-H. (2nd Ed., Sinauer Associates, 2000)
Molecular Evolution and Phylogenetics by Nei, M. and Kumar, S. (Oxford University Press, 2000)
Inferring Phylogenies by Felsenstein, J. (Sinauer Associates, 2003)
The Phylogenetic Handbook: A Practical Approach to DNA and Protein Phylogeny Ed. by Salemi, M. and Vandamme, A. (Cambridge University Press, 2003)
Bioinformatics and Molecular Evolution by Higgs, P. and Attwood, T. (Wiley-Blackwell, 2005)
Statistical Methods in Molecular Evolution Ed. by Nielsen, R. (Springer, 2005)
Computational Molecular Evolution by Yang, Z. (Oxford University Press, 2006)
Phylogenetic Trees Made Easy: A How-to Manual by Hall, B. G. (4th Ed., Sinauer Associates, 2011)
Introduction to Evolutionary Genomics by Saitou, N. (Springer, 2013)
Molecular Evolution: A Statistical Approach by Yang, Z. (Oxford University Press, 2014)
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評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
Week 6 |
4/02 |
Spring break |
Week 16 |
6/11 |
Final project presentation |
Week 17 |
6/18 |
National holiday |
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