This course will provide an introduction to the applications of bioinformatics in our everyday lives. We will begin by exploring the function of DNA and genes, the sequencing of the human genome, and the advancement of sequencing technology. We will understand how DNA mutations lead to genetic diseases, and further discuss the bioinformatic applications in personalized medicine and cancer treatment. We will also explore the diagnostic potential of liquid biopsy and noninvasive prenatal testing in detecting genetic mutations and diseases. In addition, we will discuss the role of biobanks and genome-wide association studies (GWAS) in identifying disease-causing genes, as well as the ethical and privacy issues surrounding genomic data. We will also examine how bioinformatic analyses can reveal family histories and the genetic diversity of human populations.
Throughout the course, we will watch films and engage in group discussions to enhance understanding of the course material.

本課程將介紹生物資訊學在日常生活中的應用。我們將探索DNA和基因的功能、人類基因組的定序及定序技術的進步。接著我們將了解DNA突變如何導致遺傳疾病，並進一步討論生物資訊學在個人化精準醫療和癌症治療中的應用。我們也將介紹液體活檢和產前檢測在檢測基因突變和疾病中的診斷潛力。此外，我們將討論生物資料庫和全基因組關聯研究（GWAS）在偵測致病基因中的應用，以及與臨床基因組數據的倫理及個人隱私相關問題。我們還將審視生物資訊分析如何揭示家族史及人類群體的遺傳多樣性。

在整個課程中，我們將透過觀看影片並進行小組討論，以加深對課程主題的理解。

本課程「不接受」期中停修。分組將在第二週進行。