課程資訊
課程名稱
專題討論
Seminar 
開課學期
104-1 
授課對象
生化科技研究所  
授課教師
楊啟伸 
課號
BST7000 
課程識別碼
B22 M0020 
班次
04 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一8,9(15:30~17:20) 
上課地點
農化一第六 
備註
必修4學期。與黃慶璨、張麗冠、陳進庭、林晉玄、吳承合開
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1041BST7000_04 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

專題討論 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
09/14  專題討論課程說明(楊啓伸老師) 
第2週
09/21  科學期刊和演講(林晉玄老師) 
第3週
09/28  不上課(中秋節) 
第4週
10/05  陳玨頻:博士公開演講
 
第5週
10/12  【博士班】</br>【黃柄翰】<br />Replication of Epstein–Barr Viral DNA<br /><b><i>Cold Spring Harb Perspect Biol 5:a013029 (2013).</b></i></br>【沈縵】<br />General considerations regarding the in vitro and in vivo properties of block copolymer micelle products and their evaluation. <br /><b><i>Journal of Controlled Release 210:76–83 (2015).</b></i> 
第6週
10/19  【鄧福勝】</br>Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi</br><i><b>Nature Reviews Microbiology, published online, (2015)</i></b></br>【碩士班二年級】</br>【陳則堯】</br>Inhibition of cGAS DNA Sensing by a Herpesvirus Virion Protein.</br><i><b>Cell Host & Micobe 18:333–344 (2015) </i></b> 
第7週
10/26  【簡琇羽】</br>The Extracellular Matrix Component Psl Provides Fast-Acting Antibiotic Defense in Pseudomonas aeruginosa Biofilms.</br><b><i>PLoS Pathog 9(8): e1003526.(2013) </b></i>.</br>【林俞均】<br />Dengue subgenomic RNA binds TRIM25 to inhibit interferon expression for epidemiological fitness.</br><b>i>Science. pii: aab3369. [Epub ahead of print]</b></i> (2015). 
第8週
11/02  【殷群】<br />Viral Nucleases Induce an mRNA Degradation-Transcription Feedback Loop in Mammalian Cells <br /><i><b>Cell Host & Microbe 18, 243–253 (2015)</b></i>.</br>【黃湘燕】</br>Fis overexpression enhances Pseudomonas putida biofilm formation by regulating the ratio of LapA and LapF</br><i><b>Microbiology 160:2681–2693 (2104)</i></b>
 
第9週
11/09  【張道明】</br>碩士論文公開演講</br>【翁筠婷】</br><i>In vivo</i> imaging and tracking of host–microbiota interactions via metabolic labeling of gut anaerobic bacteria</br><b><i>Nat Med. 21(9):1091-100 (2015)</b></i>.</br>【王開立】<br />An Interferon-a-Induced Tethering Mechanism Inhibits HIV-1 and Ebola Virus Particle Release but Is Counteracted by the HIV-1 Vpu Protein<br /><b><i>Cell Host Microbe. 2007 Sep 13;2(3):193-203</b></i>. 
第10週
11/16  【黃元祈】</br>Structure-Guided Design of an Anti-dengue Antibody Directed to a Non-immunodominant Epitope</br><i><b>Cell, 162:493–504 (2015)</i></b></br>【吳智宇】</br>Nucleic Acid Recognition Orchestrates the Anti-Viral Response to Retroviruses</br><i><b>Cell Host Microbe. 17(4):478-88 (2015)</i></b> 
第11週
11/23  【黃儀真】<br />Antimicrobial Photodynamic Inactivation Inhibits Candida albicans Virulence Factors and Reduces <i>in vivo</i> Pathogenicity.</br><b><i> Antimicrobial Agents and Chemotherapy 57(2013) 445-451 </b></i>.</br>【侯健睿】</br>Bacterial fight-and-flight responses enhance virulence in a polymicrobial infection.</br><i><b>Proc Natl Acad Sci U S A, 111(21):7819-24 (2014)</i></b> 
第12週
11/30  【張芝榕】</br>β-Glucan Synthase Gene Overexpression and β-Glucans Overproduction in <i>Pleurotus ostreatus</i> Using Promoter Swapping.</br><i><b>PLoS ONE 8(4): e61693, 2013.</i></b></br>【碩士班一年級】</br>【陳政良】</br>Formation and maturation of phase-separated liquid droplets by RNA-binding proteins.</br><i><b>Mol. Cell, doi:10.1016/j.molcel.2015.08.018 (2015)</i></b> 
第13週
12/07  【洪凱琳】<br />Oxidative Modification of miR-184 Enables It to Target Bcl-xL and Bcl-w</br><b><i>Molecular Cell 59:50-61 (2015)</b></i>.</br>【陳紀元】</br>DNA sense-and-respond protein modules for mammalian cells</br><i><b>Nat. Methods (2015):Advance online publication </i></b> 
第14週
12/14  【張景翔】<br />The Bacterial Curli System Possesses a Potent and Selective</br><b><i>Molecular Cell 57:445-455 (2015)</b></i>.</br>【林庭安】<br />Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis<br /><b><i>Cell. 2015 Apr 9;161(2):264-76</b></i>. 
第15週
12/21  【蔡孟羲】</br>Tuber-specific silencing of asparagine synthetase-1 reduces the acrylamide-forming potential of potatoes grown in the field without affecting tuber shape and yield</br><i><b>Plant Biotech. J. 1-12 (2012)</i></b></br>【陳昱嘉】</br>Chemosensation of Bacterial Secondary Metabolites Modulates Neuroendocrine Signaling<i><b>Cell 159:267-280 (2014)</i></b> 
第16週
12/28  【何新榮】</br>Fungal-assisted algal flocculation: application in wastewater treatment and biofuel production</br><i><b>Biotechnology for Biofuels. 8:24 (2015)</i></b></br>【胡哲銘】</br>Recombinant Spider Silk Genetically Functionalized with Affinity Domains.</br><i><b>Biomacromolecules, 15:1696&#8722;1706 (2014)</i></b> 
第17週
2016/01/04  【張煜】</br>Visual arrestin interaction with clathrin adaptor AP-2 regulates photoreceptor survival in the vertebrate retina<b><i></br>PNAS 10:9463–9468 (2013)</b></i>.</br>【荊士瑋】</br>Chemodetection and Destruction of Host Urea Allows Helicobacter pylori to Locate the Epithelium. </br><i><b>Cell Host Microbe, 18:147-56 (2015).</i></b> </br>【林小琪】</br>A Novel Mechanism for CTCF in the Epigenetic Regulation of Bax in Breast Cancer Cells</br><i><b>Neo Plasa, 15:898-912 (2013)</i></b> 
第18週
2016/01/11  【李依依】
MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes.
<i><b> Oncogenesis, 2(6):e51 (2013)</i></b></br>
【碩士班論文】</br>
蔡曉涵