課程資訊
課程名稱
高等化學生物學二
Advanced Chemical Biology (Ⅱ) 
開課學期
107-2 
授課對象
理學院  化學所化學生物學組  
授課教師
吳世雄 
課號
Chem7036 
課程識別碼
223 M1620 
班次
 
學分
3.0 
全/半年
半年 
必/選修
必修 
上課時間
星期五2,3,4(9:10~12:10) 
上課地點
化121 
備註
本課程以英語授課。
限碩士班以上 且 限本系所學生(含輔系、雙修生)
總人數上限:50人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1072Chem7036 
課程簡介影片
 
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課程概述

This courses aims to provide students with general knowledge in the synthesis of biomolecules, which is applied either to prepare small molecules to probe target DNA/proteins, or to develop efficient methods to study biological questions. Therefore seven weeks are used to cover the synthesis, while the remaining is to talk about famous examples. Students who want to take the course need to pass the undergraduate course of organic chemistry (two semester courses with at least 2 hours per week). 

課程目標
It is also recommended to have basic concept in biochemistry, at least to be aware of what are the structures of amino acids, nucleic acids and sugars. 
課程要求
 
Office Hours
 
參考書目
 
指定閱讀
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
02/22  Antibiotics (particularly for beta-Lactam) and Their Resistance by Dr. Shih-Hsiung Wu 
第2週
03/01  228 Holiday 
第3週
03/08  Preparation of Conjugate Vaccine against Pathogenic Bacteria by Dr. Shih-Hsiung Wu 
第4週
03/15  Natural Products – Classification, Biosynthesis and Drug Discovery by Dr. Hsiao-Ching Lin 
第5週
03/22  Natural Products – Classification, Biosynthesis and Drug Discovery by Dr. Hsiao-Ching Lin 
第6週
3/29  Anti-Amyloid Peptide Therapy, Peptide Drug and Alzheimer’ s disease (or protein folding and neurodegenerative diseases) by Dr. Rita PY Chen 
第7週
04/05  No Class-Observe the Tomb Sweeping Day 
第8週
4/12  Natural Products – Classification, Biosynthesis and Drug Discovery by Dr. Hsiao-Ching Lin 
第9週
04/19  Anti-Amyloid Peptide Therapy, Peptide Drug and Alzheimer’ s disease (or protein folding and neurodegenerative diseases) by Dr. Rita PY Chen 
第10週
04/26  Anti-Amyloid Peptide Therapy, Peptide Drug and Alzheimer’ s disease (or protein folding and neurodegenerative diseases) by Dr. Rita PY Chen 
第11週
05/03  Midterm Exam 
第12週
05/10  Anti-Virus and Anti-Cancer Drug Discovery by Dr. Po-Huang Liang 
第13週
05/17  Anti-Virus and Anti-Cancer Drug Discovery by Dr. Po-Huang Liang 
第14週
05/24  Anti-Virus and Anti-Cancer Drug Discovery by Dr. Po-Huang Liang 
第15週
05/31  Combinatorial Chemistry-Parallel synthesis & High-Throughput Drug Screening by Dr. Wenshan Li 
第16週
06/07  Holiday ( Dragon Boat Festival) 
第17週
06/14  Rational Design of Enzyme Inhibitors-Drug design: identification of a pharmacophore and lead optimization Or Specific labeling on biomolecules-Case study by Dr. Wenshan Li 
第18週
06/21  Final Exam