課程資訊
課程名稱
分子親緣關係學
Molecular Evolution: A Phylogenetic Approach 
開課學期
110-2 
授課對象
理學院  海洋生物及漁業組  
授課教師
陳韋仁 
課號
Ocean5143 
課程識別碼
241 U6400 
班次
 
學分
2.0 
全/半年
半年 
必/選修
選修 
上課時間
星期四3,4(10:20~12:10) 
上課地點
海研110教室 
備註
本課程以英語授課。
總人數上限:10人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1102Ocean5143_ 
課程簡介影片
 
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課程概述

This is a basic and practical course intended for senior undergraduate and graduate students with already strong knowledge in basic biology. Students who are interested in any fields in biology are all welcome, because all of the biological phenomena are the product of the evolution. In this course, we will focus on how the phylogenetic approach can be used to provide a meaningful interpretation of biodiversity and a comprehensive understating of history and mechanisms of evolution of our studying organisms. The course is designed for hand-on work with the empirical data. We will also use well-developed software but we do not need skills in computer programming for our practical work. 

課程目標
Students will expect to
1. obtain the basic knowledge and related applications of the phylogenetics
2. learn how to build a phylogenetic tree
3. acquire the ability to design and execute related research projects (systematics, Biodiversity, Evolution, etc.) 
課程要求
Students must have already strong knowledge in basic biology and basic knowledge in genetics and molecular biology. 
預期每週課後學習時數
 
Office Hours
另約時間 
參考書目
1.Molecular Evolution: A Phylogenetic Approach
by Roderick D.M. Page, Edward C. Holmes
ISBN: 978-0-86542-889-8
http://as.wiley.com/WileyCDA/WileyTitle/productCd-0865428891.html
2.Inferring phylogenies
By Joseph Felsenstein
http://www.sinauer.com/detail.php?id=1775
3.Phylogenetic trees made easy : a how-to manual / Barry G. Hall
By Barry G. Hall
http://www.sinauer.com/hall/3e/ 
指定閱讀
待補 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
學生學習態度 
10% 
 
2. 
作業成積 
10% 
 
3. 
期中考筆試成積 
20% 
 
4. 
期末報告內容 
60% 
Oral presentation and writing report 
 
課程進度
週次
日期
單元主題
第1週
2/17  Introduction-1 
第2週
2/24  Introduction-2 
第3週
3/03  Tree 
第4週
3/10  From DNA to Diversity 
第5週
3/17  Measuring genetic change and models of molecular evolution 
第6週
3/24  Inferring Molecular Phylogeny-I 
第7週
3/31  Inferring Molecular Phylogeny-II 
第8週
4/07  Bayesian inference of phylogeny 
第9週
4/14  Data collection and Introductions to the basic phylogenetic tools (editing and aligning the sequences) 
第10週
4/21  Midterm exam 
第11週
4/28  Introductions to the phylogenetic tools (PAUP; RAxML; CIPRES) 
第12週
5/05  Phylogenetic applications 
第13週
5/12  MrBayes and BEAST (practice work) -I 
第14週
5/19  MrBayes and BEAST (practice work) -II 
第15週
5/26  Invited talk (Dr. Hsin Lee?) or Group discussion 
第16週
6/02  Final report presentation 
第18週
6/16  Deadline for final report submission to prof. Chen