課程資訊
課程名稱
 量性研究方法論
Quantitative Research Methodology 
開課學期
 105-1 
授課對象
 醫學院  護理學研究所  
授課教師
 孫秀卿 
課號
 NURSE8028 
課程識別碼
 426ED4420 
班次
  
學分
 2 
全/半年
 半年 
必/選修
 必修 
上課時間
 星期一6,7(13:20~15:10) 
上課地點
 護討論室1 
備註
 本課程以英語授課。與賴裕和、蔡劭瑜、吳佳儀合開
限博士班
總人數上限：20人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/1051NURSE8028_ 
課程簡介影片
 
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課程概述

This class is to prepare doctoral students to develop advanced knowledge, logical thinking and practical abilities in designing, conducting and implementing quantitative research. Students are expected to train themselves through massive reading, interactive discussion, original research paper critique and research project design and presentation. Knowledge and skills related to quantitative research, including measurements, data collection and scientific writing, etc. will be discussed in this class. Critical and logical thinking and problem-solving abilities in developing quantitative research are expected after finishing this class.  

課程目標
 At completion of the course, the students are prepared to:
1. Demonstrate knowledge of various designs and methods in quantitative research.
2. Identify methodological issues pertinent to quantitative research.
3. Demonstrate the skills in data collection, analysis, and reporting techniques in
quantitative research.
4. Apply principles of instrument development to current measurement problems.
5. Evaluate the quality and relevance of quantitative research.
 
課程要求
 ★ Submit questions for discussion: Please email at least 1 question to all class members by midnight prior to the day of class.
★ Distribute 1 reference article to class members one week prior to the presentation.
 
預期每週課後學習時數
  
Office Hours
  
指定閱讀
 待補 
參考書目
 Jadad, A. R., & Enkin, M. W. (2007). Randomized controlled trials: Questions, answer
answers, and musings (2nd ed.). Oxford: Blackwell Publishing.
Behling, O., & Law, K. S. (2000). Translating questionnaires and other research instr
instruments: Problems and solutions. Thousand Oaks, CA: Sage.
Brink, P. J., & Wood, M. J. (1998). Advanced design in nursing research (2nd ed.)
ed.). Thousand Oaks, CA: Sage
Burns, N. & Grove, S. K. (2013). The practice of nursing research: Appraisal, syn
synthesis, and generation of evidence (7th ed.). Philadelphia, PA: W.B. Sau
Saunders.
Menard, S. W. (2002). Longitudinal research (2 nd ed.). Thousand Oaks, CA: Sage.
Polit, D. F., & Beck, C. T. (2011). Nursing Research: Generating and assessing e
evidence for nursing practice (9th ed.). Philadelphia: Lippincott William & W
Wilkins.
Sidani, S., & Braden, C. J. (1998). Outcomes-related factor. In Souraya Sidani
(Ed.), Evaluating nursing interventions: A theory driven approach (pp. 138-160). Thousand Oaks, CA: Sage.
Streiner, D. L., & Norman, G. R. (2008). Health measurement scales: A practical guide to their development and use. (4 th ed.). Oxford: Oxford Medical Publications.
Vogt, W. P. (2011). Dictionary of statistics and methodology: a nontechnical guide for the social science (4 th ed.). Thousand Oaks, CA: Sage.
Waltz, C. F., Strickland, O. L., & Lenz, E. R. (2010). Measurement in nursing and health research (4 rd ed.). New York: Springer.

160). Thousand Oaks, CA: Sage.
Streiner, D. L., & Norman, G. R. (2008). Health measurement scales: A practical gui
guide to their development and use. (4 th ed.). Oxford: Oxford Medical Pub
Publications.
Vogt, W. P. (2011). Dictionary of statistics and methodology: a nontechnical gu
guide for the social science (4 th ed.). Thousand Oaks, CA: Sage.
Waltz, C. F., Strickland, O. L., & Lenz, E. R. (2010). Measurement in nursing a
and health research (4 rd ed.). New York: Springer.
台灣護理學會編譯•（2003）•科學誠正指引第二版•台北：台灣護理學會。
國家衛生研究院論壇生命暨醫療倫理委員會•(2004)•知情同意：常見問答集Q & A•台北：
北：國家衛生研究院。

Linkage from Theory to Research and Practice
Avant, K. C. (1991). The theory-research dialectic: A different approach. N
Nursing Science Quarterly, 4(1), 2.
Benner, P. (2000). Links between philosophy, theory, practice, and research.
Canadian Journal of Nursing Research, 32(2), 7-13.
Burns, N. & Grove, S. K. (2008). The practice of nursing research: Appraisal, S
Synthesis, and Generation of Evidence (6th ed.). Philadelphia, PA: W.B. S
Saunders.
Chen, C. C-H. (2005). A framework for studying the nutritional health of
community-dwelling elders. Nursing Research, 54, 13-21.
Dulock, H. L., & Holzemer, W. L. (1991). Substruction: Improving the linkage
from theory to method. Nursing Science Quarterly, 4(2), 83-87.
McQuiston, C. M., & Campbell, J. C. (1997). Theoretical substruction: A guide
for theory testing research. Nursing Science Quarterly, 10(3), 117-123.
Radwin, L., & Fawcett, J. (2002). A conceptual model-based programme of nursing
research: Retrospective and prospective applications. Journal of Advanced
Nursing, 40, 355-360.
Im, E. O., & Chang, S. J. (2012). Current trends in nursing theories. Journal
of Nursing Scholarship, 44(2), 156-164.

Experimental & Quasi-Experimental Designs
Bench, S., Day, T., & Metcalfe, A. (2013). Randomised controlled trials: an
introduction for nurse researchers. Nurse Researcher, 20(5), 38-44.
Brown, S. J. (2002). Nursing intervention studies: A descriptive analysis of
issues important to clinicians. Research in Nursing & Health, 25(4), 317-327.
Conn, V. S., Rantz, M. J., Wipke-Tevis, D. D., & Maas, M. L. (2001). Designing e
effective
nursing interventions. Research in Nursing & Health, 24(5), 433-442.
Downs, S.H., & Black, N. (1998). The feasibility of creating a checklist for t
the assessment of
the methodological quality both of randomized and non-randomized studies of
health care interventions. Journal of Epidemiology and Community Health, 52,
377-384.
Fogg, L., & Gross, D. (2000). Threats to validity in randomized clinical
trials. Research in Nursing & Health, 23(1), 79-87.
Gross, D, & Fogg, L. (2001). Clinical trials in the 21st century: The case for
participant-centered research. Research in Nursing & Health, 24, 530-539.
Lindsay, B. (2004). Randomized controlled trials of socially complex nursing
interventions: Creating bias and unreliability. Journal of Advanced Nursing, 45
(1), 84-94.
Polit, D. F., Gillespie, & B. M. (2010). Intention-to-treat in randomized
controlled trials: recommendations for a total trial strategy. Research in
Nursing & Health, 33(4), 355-368.
Schumacher, K. L., Koresawa, S., West, C., Dodd, M., Paul, S. M., Tripathy, D.,
et al. (2005). Qualitative research contribution to a randomized clinical
trial. Research in Nursing & Health, 28, 268-280.
Siebens, H., Aronow, H., Edwards, D., & Gbasemi, Z. (2000). A randomized
controlled trial of exercise to improve outcomes of acute hospitalization in
older adults. Journal of the American Geriatric Society, 48, 1545-1552.

Issues in Quantitative Design and Measurement

Azuero, A., Pisu, M., McNees, P., Burkhardt, J., Benz, R., & Meneses, K. (
(2010). An
application of longitudinal analysis with skewed outcomes. Nursing Research,
59, 301-307.
Banerjee, M., & Fielding, J. (1997). Interpreting Kappa values for two-observer n
nursing
diagnosis data. Research in Nursing & Health, 20, 465-470.
Bernal, H., Wooley, S., & Schensul, J. J. (1997). The challenge of using Likert-type scales with low
type scales with low-literate ethnic population. Nursing Research, 46(3), 179-181.
Goodwin, L. D. (1996). Determining cut
181.
Goodwin, L. D. (1996). Determining cut-off scores. Research in Nursing &
Health, 19, 249-256.
Goodwin, L. D., & Goodwin, W. L. (1991). Estimating construct validity. R
Research in
Nursing & Health, 14, 235-243.
Hinds, P. S., Schum, L. & Srivastava, D. K. (2002). Is clinical relevance s
sometimes lost in
summative scores. Western Journal of Nursing Research, 24, 345-353.
Higgins, P. A., & Daly, B. J. (1999). Research methodology issues related to i
interviewing the
mechanically ventilated patient. Western Journal of Nursing Research, 21, 773-784.
Hulley, S. B., Cummings, S. R., & Bowner, W. S. (2001). Implementing the study: Pretesting,
quality control, and protocol revisions. Designing Clinical Research. (2nd ed.). Philadelphia: Lippincott Williams & Wilkins, 259
784.
Hulley, S. B., Cummings, S. R., & Bowner, W. S. (2001). Implementing the study: P
Pretesting,
quality control, and protocol revisions. Designing Clinical Research. (2nd
ed.). Philadelphia: Lippincott Williams & Wilkins, 259-273. (e-book, 2007)
Hughes, L. C., & Preski, S. (1997). Using key informant methods in
organizational survey research: Assessing for informant bias. Research in
Nursing & Health, 20, 81-92.
Jones, E. G., & Kay, M. (1992). Instrumentation in cross-cultural research. N
Nursing Research,
41(3), 186-188.
King, K. M. (2003). Is there a “representative” sample? Western Journal of
Nursing Research, 25(1), 5-7.
Knapp, T. R., & Brown, J. K. (1995). Ten measurement commandments that often
should be broken. Research in Nursing & Health, 18, 465-469.
Knapp, T. R. (1991). Coefficient alpha: Conceptualizations and anomalies.
Research in Nursing & Health, 14, 457-460.
Kneipp, S. M., & Yarandi, H. N. (2002). Complex sampling designs and s
statistical issues in
secondary analysis. Western Journal of Nursing Research, 24(5), 552-566.
Krause, M. R., Serlin, R. C., Ward, S. E., Rony, Y. Z, Ezenwa, M. O., & Naab, F
F. (2010).
Testing Mediation in Nursing Research: Beyond Baron and Kenny. Nursing
Research, 59, 288-294
Lee, J. W., Jones, P. S., Mineyama, Y., & Zhang, X. E. (2002). Cultural
differences in responses to a Likert scale. Research in Nursing & Health, 25
(1), 295-306.
Lobo, M. L. (1993). Code books: A critical link in the research process.
Western Journal of Nursing Research, 15(3), 377-385.
Lorig, K., Gonzalez, V. M., Ritter, P., & Brey, V. N. D. (1997). Comparison of
three methods of data collection in an urban Spanish-speaking population.
Nursing Research, 46(6), 230-234.
Lynn, M. R. (1986). Determination and quantification of content validity.
Nursing Research, 35(6), 382-385.
McKinley, S., Coote, K., & Stein-Parbury, J. (2003). Development and testing of
a face scale for the assessment of anxiety in critically ill patients. Journal
of Advanced Nursing, 41(1), 73-99.
Patrician, P. A. (2002). Multiple imputation for missing data. Research in
Nursing & Health, 25 (1), 76-84.
Phillips, L. R., de Hernandez, I. L., & de Ardon, E. T. (1994). Focus on
psychometrics: Strategies for achieving cultural equivalence. Research in
Nursing & Health, 17, 149-154.
Polit, D. F., & Beck, C. T. (2010). Generalization in quantitative and
qualitative research: Myths and strategies. International Journal of Nursing
Studies, 47, 1451-1458.
Stewart, B. J., & Archbold, P. G. (1992). Nursing intervention studies require
outcome measures that are sensitive to change: Part one: Research in Nursing &
Health, 15, 477-481.
Stewart, B. J., & Archbold, P. G. (1993). Nursing intervention studies require
outcome measures that are sensitive to change: Part two: Research in Nursing &
Health, 16, 77-81.
Weinstein, J. N., & Deyo, R. A. (2000). Clinical research issues in data
collection. Spine, 25(24), 3104-3109.
Wynd, C. A., Schmidt, B., & Schaefer, M. A. (2003). Two quantitative approaches
for estimating content validity. Western Journal of Nursing Research, 25(5),
508-518.
Youngblut, J. M., & Casper, G. R. (1993). Single-item indications in nursing
research. Research in Nursing & Health, 16, 459-465.
林正祥•(1994)•研究設計之樣本數決定•中華民國公共衛生學會雜誌，12(3) ，282-290
290。
盧成皆•(1996)•護理研究中常遇到的統計問題實例探討•護理研究，4(3) ，298-306。
盧成皆•(1997)•線性複迴歸所需樣本數目之討論•護理研究，5(4)，377-383。
盧成皆、林京芬（1998）•關於Cronbach's Alpha 的使用與闡釋•護理研究，6(1)，82-88
88。

Instrument Translation and Testing
Chang, A. M., Chau, J. P. C., & Holroyd, E. (1999). Translation of
questionnaires and issues of equivalence. Journal of Advanced Nursing, 29, 316-322.
DeVellis, F. R. (2012). Scale development : Theory and applications (3rd Ed). Thousand Oaks.Sage, Carlifornia
Yu, D. S. F., Lee, D. T. F., & Woo, J. (2004). Issues and challenges of instrument translation. Western Journal of Nursing Research, 26, 307
322.
DeVellis, F. R. (2012). Scale development : Theory and applications (3rd Ed). T
Thousand Oaks.Sage, Carlifornia
Yu, D. S. F., Lee, D. T. F., & Woo, J. (2004). Issues and challenges of
instrument translation. Western Journal of Nursing Research, 26, 307-320.
葉美玲、陳興夏•（1998）•測量工具翻譯與效度•長庚護理, 9(1), 64-68。

Academic Writing
Becker, P. T. (2004). What happens to my manuscript when I send it to Research
in Nursing & Health. Research in Nursing & Health, 27, 379-381.
Broome, M. E. (2003). Scientific integrity: The cornerstone of knowledge.
Journal of Neuroscience Nursing, 35(1), 56-59.
Dallas, C. M., Norr, K., Dancy, B. L., Kavanaugh, K., & Cassata, L. (2005). An
example of a successful research proposal: Part I. Western Journal of Nursing
Research, 27(1), 50-72.
Dallas, C. M., Norr, K., Dancy, B. L., Kavanaugh, K., & Cassata, L. (2005). An
example of a successful research proposal: Part II. Western Journal of Nursing
Research, 27(2), 210-231.
Froman, R. D. (2004). Numbers, numbers everywhere. Research in Nursing &
Health, 27, 145-147.
Higdon, J. & Topp, R. (2004). How to develop a budget for a research proposal.
Western Journal of Nursing Research, 26, 922-929.
Locher, J. L., Robinson, C. O., Roth, D. L., Ritchie, C. S., & Burgio, K. L.
The effect of presence of others on caloric intake in homebound older adults.
Journal of Gerontology: Medical Sciences, 60A, 1475-1478.
Lusk, S. L. (2004). Developing an outstanding grant application. Western
Journal of Nursing Research, 26, 367-373.
Ness, V., Duffy, K., McCallum, J., & Price, L. (2014). Getting published:
Reflections of a collaborative writing group. Nurse Education Today, 34(1), 1-5.
Owen, S. V. (2005). The significance of significance. Research in Nursing &
Health, 28, 281-282.
洪祖培、陳錦得•（1999）•醫學論文的列名準則與責任•台灣醫學，3(5), 543-549。
 
評量方式
(僅供參考)
    
課程進度
週次
日期
單元主題
Week 2
 9/19  Linkage Among Theory, Research & Practice 
Week 3
 9/26  Survey Design – Cross-sectional Design 
Week 4
 10/03  Longitudinal Design 
Week 5
 10/10  Holiday 
Week 6
 10/17  Designing Intervention Studies 
Week 7
 10/24  Assessing Quality of Intervention Research  
Week 8
 10/31  Outcome research 
Week 9
 11/07  Measurement Theory: Reliability & Validity 
Week 10
 11/14  Instrument Development & Translation  
Week 11
 11/21  Sampling & Sample Size 
Week 12
 11/28  Measuring Bio-Indicators in Nursing Research 
Week 13
 12/05  Academic Writing 
Week 14
 12/12  Article Critique Presentation (I) 
Week 15
 12/19  Article Critique Presentation (II) 
Week 16
 12/26  Final Presentation (I) 
Week 17
 1/02  Holiday 
Week 18
 1/9  Final Presentation (II) & Course Evaluation