本課程內容如下:
*Introduction: brief history of genetics
*Comparative Gene-Expression Analysis I: Hybridization-based techniques
-- In-house spotted arrays
-- Prespotted array (inkjet print)
-- Photolithograph
-- Maskless array synthesis
-- BeadChip
-- MicroArray Quality Control (MAQC) Project

*Comparative Gene-Expression Analysis II: PCR-based techniques
-- RT-PCR

*Comparative Gene-Expression Analysis III: Sequence-based techniques
-- Next generation sequencing

*Genomic approaches to study:
-- Gene expression profiling
-- Single nucleotide polymorphism (SNP), copy number variation (CNV), loss of heterozygosity (LOH)
-- DNA-protein interaction
-- Epigenomic: DNA Methylation
-- Epigenomic: noncoding RNA
-- Metagenomics
-- Carcinogenesis and treatment