課程資訊
課程名稱
 神經退化研究論著選讀
Neurodegeneration Seminar 
開課學期
 104-2 
授課對象
 學程  神經生物與認知科學學程  
授課教師
 詹智強 
課號
 Physio7040 
課程識別碼
 441 M3900 
班次
  
學分
 2 
全/半年
 半年 
必/選修
 選修 
上課時間
 星期三7,8(14:20~16:20) 
上課地點
 基醫1003 
備註
 本課程中文授課,使用英文教科書。
總人數上限：25人
外系人數限制：5人 
  
課程簡介影片
 
核心能力關聯
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課程大綱
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課程概述

本課程內容以最近5年神經退化研究(Neurodegeneration)相關的期刊論文為主。課程依據下列主題，找尋適當的期刊論文研讀與討論
This course is based on lectures and discussions on recent research in the field of neurodegeneration. Lectures and discussions explore the pathology, molecular mechanisms, and therapeutic aspects of neurodegenerative disorders. Topics include the intracellular mechanisms regulating neuron maintenance, as well as neurodegenerative conditions such as Parkinson's disease, Alzheimer's disease, Peripheral neuropathies, etc. Through literature reading and group discussion, the students should understand the recent discoveries in the field of neurodegeneration. 

課程目標
 The lectures and discussions will focus on recent research (within 5 years) in the field of neurodegeneration. Students will be assigned relevant paper according to the topics listed below for discussion.
1. Introduction: Overview of Neurodegeneration
2. Neurodegenerative Disorders- Molecular Mechanisms
- Genetic Links
- Intracellular Mechanisms: Deranged Calcium Signaling
- Intracellular Mechanisms: Deregulated Protein Degradative Pathways
- Intracellular Mechanisms: Reduced Axonal Transport
3. Programmed Cell Death and Neurodegeneration
- Apoptosis
- Autophagy
4. Intracellular Trafficking and Neurodegeneration
5. Pathology of Neurodegenerative Disorders
6. Therapeutics for Neurodegenerative Disorders 
課程要求
 不遲到早退, 積極參與課堂間的報告與討論
Students are expected to give oral presentations in class based on a selected journal article from the reading list. There is one final exam or oral presentation. Attendance is required at all class meetings. 
預期每週課後學習時數
  
Office Hours
  
指定閱讀
  
參考書目
 Selected papers within 5 years from high-profile journals, with focus on the molecular mechanisms of neurodegeneration. 
評量方式
(僅供參考)
    
課程進度
週次
日期
單元主題
無資料