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課程名稱 |
臨床藥品動態學
Clinical Pharmacokinetics |
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開課學期 |
103-1 |
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授課對象 |
醫學院 藥學系 |
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授課教師 |
林淑文 |
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課號 |
CliPhm7003 |
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課程識別碼 |
451 M0100 |
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班次 |
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學分 |
2 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期四7,8(14:20~16:20) |
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上課地點 |
基醫406 |
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備註 |
限本所學生與藥學系五年級以上學生修課。與胡幼圃、林君榮、林慧玲、沈麗娟合開
限學士班五年級以上
總人數上限：40人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1031CliPhm7003_ |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
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課程大綱
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課程概述 |
CLINICAL PHARMACOKINETICS IS A CONTINUED COURSE FOR BIOPHARMACEUTICS AND PHARMACOKINETICS. SOME OF THE INFORMATION AND CONCEPTS FROM MATHEMATICS AND ELEMENTARY PHARMACOKINETICS WILL BE REVIEWED OR DEVELOPED AS NEEDED, BUT THE BALANCE OF PREREQUISITE MATERIAL WILL BE THE STUDENT’S RESPONSIBILITY. READINGS AND HOMEWORK WILL BE ASSIGNED, OR MAY BE SUGGESTED TO IMPROVE THE LEARNING EFFICIENCY OF STUDENTS. |
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課程目標 |
THE MAJOR PURPOSE OF THIS COURSE IS TO TEACH STUDENTS HOW TO SOLVE PHARMACOKINETIC AND/OR PHARMACODYNAMIC PROBLEMS ENCOUNTERED IN CLINICAL PRACTICE |
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課程要求 |
PREREQUISITES: BIOPHARMACEUTICS AND PHARMACOKINETICS. STUDENTS SHOULD BE FAMILIAR WITH BASIC CONCEPTS OF BIOPHARMACEUTICS AND PHARMACOKINETICS (I.E., THE MEANINGS OF ADME AND RELATED APPLICATIONS) |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
WAGNER, FUNDAMENTAL OF CLINICAL PHARMACOKINETICS, 1975
ROWLAND AND TOZER, CLINICAL PHARMACOKINETICS, CONCEPTS AND APPLICATIONS, 1995
IN ADDITION TO THE RECOMMENDED TEXTS ABOVE, READINGS FROM OTHER BOOKS, REVIEW ARTICLES OR THE PRIMARY LITERATURE MAY BE ASSIGNED OR RECOMMENDED BY EACH INSTRUCTOR. SOME OF THE FACULTY MAY ALSO PROVIDE HANDOUT NOTES AS A GUIDE OR SUPPLEMENT TO THEIR LECTURES.
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
林淑文老師 |
28% |
課前作業、課堂討論、課後隨堂小考 |
2. |
林君榮老師 |
24% |
課堂討論及課後指定作業 |
3. |
胡幼圃老師 |
24% |
書面報告 |
4. |
林慧玲老師 |
6% |
課前作業、期末指定作業 |
5. |
沈麗娟老師 |
18% |
課前作業、期末指定作業 |
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週次 |
日期 |
單元主題 |
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第1週 |
9/18 |
Course introduction |
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第2週 |
9/25 |
Pharmacogenetics and individualization |
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第3週 |
10/02 |
Drug-drug Interaction |
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第4週 |
10/09 |
Clinical application of population PK/PD analysis |
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第5週 |
10/16 |
Clinical Pharmacokinetics of Immunosuppressants |
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第6週 |
10/23 |
Clinical pharmacokinetics of CNS drugs |
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第7週 |
10/30 |
PK & PD of Antimicrobial agents |
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第8週 |
11/06 |
(1) Aminoglycosides
(2) Glycopeptides |
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第9週 |
11/13 |
Antifungal agents |
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第10週 |
11/20 |
Clinical pharmacokinetics and medication use in pediatric patients |
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第11週 |
11/27 |
Clinical Pharmacokinetics and chemotherapy |
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第12週 |
12/04 |
(1) TDM in special populations: pregnancy, and cancer patients
(2) Effect of Hepatic Disease on Clinical Pharmacokinetics (I) |
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第13週 |
12/11 |
Effect of Hepatic Disease on Clinical Pharmacokinetics (II) |
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第14週 |
12/18 |
Clinical Pharmacokinetics in cardiac failure patients and cardiovascular drugs |
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第15週 |
12/25 |
Plasma Protein Binding on Clinical Pharmacokinetics |
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第16週 |
1/01 |
開國紀念日 |
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第17週 |
1/08 |
Clinical pharmacokinetics in geriatrics |