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課程名稱 |
當神經生理學遇見光遺傳學
When neurophysiology meets optogenetics |
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開課學期 |
106-1 |
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授課對象 |
醫學院 腦與心智科學研究所 |
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授課教師 |
姚皓傑 |
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課號 |
GIBMS7014 |
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課程識別碼 |
454 M0380 |
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班次 |
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學分 |
2.0 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期三6,7(13:20~15:10) |
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上課地點 |
基1203 |
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備註 |
與王培育、吳恩賜、黃憲松、曾明宗合授
限本系所學生(含輔系、雙修生)
總人數上限：30人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1061GIBMS7014_ |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
Optogenetics, chosen as the "Method of the Year" in 2010 by Nature Methods and highlighted in the article on “Breakthroughs of the Decade” in Science, has revolutionized the way neurophysiologists study the function of neural circuits. Optogenetic approach is a powerful research approach to map neural circuits and study their functional roles. It is the combination of genetic and optical methods to allow reversibly control neuronal activity in targeted cells or circuits of living brain in the millisecond timescale. The field of optogenetics has made remarkable progress in mapping functional neural circuits and shown tremendous impact on neurophysiology research. The course aims to enable students to understand the concepts of research questions, methodology and experimental designs through reading important optogenetic research literature focusing on the neurophysiology roles of neural circuits. |
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課程目標 |
The primary goal of the course is to provide students with a broad understanding of how to employ optogenetics in mouse model system to investigate physiology function of neural circuits, and help students develop an appreciation of the neural basis of complex neural activity. |
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課程要求 |
Preparation and participation: students taking this course will be required to do assigned literature reading each week; to present assigned literature; and take an active part in classroom discussions.
Each week, all students will be required to do the “essential reading” as uploaded in Dropbox. In the first 6 weeks, the instructor will lead the reading and the discussion of assigned literature to help students understand the basics of neurophysiology and optogenetics. In the following 12 weeks, two individual students will be given responsibility to summarize the argument of that week’s assigned literature.
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
待補 |
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參考書目 |
待補 |
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
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90% |
The quality and extent of students’ participation in class, together with the individual student’s presentation, will count for 90% of the final grade. |
2. |
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10% |
Each student will be required to finish a single page of student evaluation report on the design of the course and to provide feedback to the instructor for future adjustment. The report will count for the remaining 10% of the grade. The report is due on the last week of the course. |
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