課程資訊
課程名稱
微流體現象及應用
Fundamentals and Applications of Microfluidics 
開課學期
100-2 
授課對象
工學院  化學工程學研究所  
授課教師
趙 玲 
課號
ChemE5047 
課程識別碼
524 U2140 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期一7,8,9(14:20~17:20) 
上課地點
新401 
備註
化工選修課程。
總人數上限:20人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1002microfluidics 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

課程名稱:微流體現象及應用(Fundamentals and Applications of Microfluidics)
開課學期:100-2
開課系所:工學院 化學工程學系
授課教師:趙玲
課號:
課程識別碼:
學 分:3
必/選修:選修
授課對象:大三、大四、研究生
總人數上限:30人
備註:以中文授課為原則,使用英文教科書及隨堂講義,選修課程。

課程概述:
The objective of this course is to provide an overview of phenomena in microfluidics and summarize the major applications of microfluidics in separation, reaction, and sensing techniques. The fluids at microscale have some special phenomena, because surface tension, energy dissipation and fluidic resistence start to dominate the systems. Many innovative techniques for separation, reaction, sensing have been developed by exploiting these phenomena. This course also intends to show students how to apply many traditional chemical engineering fundamentals, such as transport phenomena, thermodynamics, kinetics to microscale events.

課程內容:
1. Introduction to microfluidics (3hrs)
2. General fabrication techniques (3hrs)
3. Fluorescence techniques to characterize events in microfluidics (6hrs)
4. Fluid kinematics and hydraulic circuit analysis in microchannels (3hrs)
5. Dispersion, patterning, and mixing in microfluidics (6hrs)
6. Microchip chemical separations (6hrs)
7. Microchip reactors (3hrs)
8. Surface forces in microfluidics (3hrs)
9. Species and charge transport in microchannel (3hrs)
10. Electrostatics, electrodynamics and electroosmosis (6 hrs)



主要教材:
1. Micro- and Nanoscale Fluid Mechanics: Transport in Microfluidic Devices, Brian Kirby, Cambridge University Press, 2010
2. Fundamentals and Applications of Microfluidics, Nam-Trung Nguyen, Steven T. Wereley, Artech House Inc., 2006

其他參考書目:
1. Physics and Applications of Microfluidics in Biology, David J. Beebe, Glennys A. Mensing, and Glenn M. Walker, Annu. Rev. Biomed. Eng. 2002 4:261–286
2. Optical fluorescence microscopy: from the spectral to the nano dimension, edited by Alberto Diaspro, Springer-Verlag Berlin Heidelberg, 2011
3. www.olympusmicro.com/primer/techniques/fluorescence/fluorhome.html
4. Low Reynolds Number Hydrodynami 

課程目標
The objective of this course is to provide an overview of phenomena in microfluidics and summarize the major applications of microfluidics in separation, reaction, and sensing techniques. The fluids at microscale have some special phenomena, because surface tension, energy dissipation and fluidic resistence start to dominate the systems. Many innovative techniques for separation, reaction, sensing have been developed by exploiting these phenomena. This course also intends to show students how to apply many traditional chemical engineering fundamentals, such as transport phenomena, thermodynamics, kinetics to microscale events, and use it as an example showing how to relate these fundamentals to research problems.

outlines:
1.Introduction to microfluidics (3hrs)
2.General fabrication techniques (3hrs)
3.Fluorescence techniques to characterize events in microfluidics (6hrs)
4.Fluid kinematics and hydraulic circuit analysis in microchannels (3hrs)
5.Dispersion, patterning, and mixing in microfluidics (6hrs)
6.Microchip chemical separations (6hrs)
7.Microchip reactors (3hrs)
8.Surface forces in microfluidics (3hrs)
9.Species and charge transport in microchannel (3hrs)
10.Electrostatics, electrodynamics and electroosmosis (6 hrs)
 
課程要求
 
預期每週課後學習時數
 
Office Hours
 
參考書目
 
指定閱讀
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
2/20  introduction 講義 
第3週
3/05  Microfabrication 
第4週
3/12  fluid mechanics in microchannels 
第5週
3/19  microfluidic flow control 
第6週
3/26  patterning, mixing and dispersion 
第7週
4/02  Formation of Droplets in Microchannel 
第8週
4/09  Reaction networks--請一併帶上週講義 
第9週
4/16  Separations in Microchannels 
第10週
4/23  Heat Transfer in Microchannels_請一併帶上週講義  
第11週
4/30  Transport in Electrolyte Solutions  
第12週
5/07  Electrokinetic mixing and pumps 
第13週
5/14  Biosensor-part 1 
第14週
5/21  no class 
第15週
5/28  Introduction to the topics of final reports--please print out the paper(s) you are interested in listed on the right.  
第16週
6/04  1. point of care 演講影片
2. 分組討論--請印下討論單或帶你的電腦直接打字於檔案中 
第17週
6/11  分組討論--請印下討論單或帶你的電腦直接打字於檔案中