課程名稱 |
分解性生醫材料 Degradable Biomaterials |
開課學期 |
106-2 |
授課對象 |
工學院 醫學工程學研究所 |
授課教師 |
黃義侑 |
課號 |
Biomed7015 |
課程識別碼 |
548 M0310 |
班次 |
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學分 |
3.0 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四2,3,4(9:10~12:10) |
上課地點 |
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備註 |
本課程中文授課,使用英文教科書。教室:基醫507 總人數上限:25人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1062Biomed7015_ |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
一、課程簡介: 學分數:3 學分
Biodegradable (and/or bioabsorbable) biomaterials are widely used in sutures, bone plates, guiding of growth of tissues, drug delivery systems and other types of prostheses. In drug delivery systems, such polymers offer the great advantage of enabling site-specific or systemic administration of pharmaceutical agents without the need for subsequent retrieval of the delivery system. This course will provide a board spectrum of biodegradable polymers, ranging from synthesis, characterization, manufacturing… to medical applications. It will be useful to students who are new to the field and would like to understand more about the various properties and medical applications of biodegradable polymers.
課程內容:包括
1. Introduction: Classification and mechanisms of biodegradation.
2. Biodegradable polyesters: Lactide/glycolide polymers
3. Biodegradable polyesters and tissue engineering
4. Polyanhydrides
5. Poly--Caprolactone and its copolymers
6. Poly(ortho esters)
7. Polyphosphazenes as new biomedical and bioactive materials
8. Pseudopoly(amino acids)
9. Natural biodegradable polymers: Albumin, collagen, and chitin/chitosan
10. Collagen and artificial skin
11. Liposome: Preparation and characterization
12. Medical applications of liposomes: Drug delivery and gene therapy
二、先修課程:無
三、參考書目:
1. Chasin M and Langer R: Biodegradable Polymers as Drug Delivery Systems. Marcel Dekker, 1990, New York.
2. Hollinger JO: Biomedical Applications of Synthetic Biodegradable Polymers. CRC Press, 1995, Boca Raton
3. Lanza RP, Langer R and Vacanti J: Principles of Tissue Engineering. Academic Press, 2000, San Diego.
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課程目標 |
This course will emphasize on the green plastcs, biodegradable macromolecules and polymers. That will be useful to students who are new to the field and would like to understand more about the various properties and medical applications of biodegradable polymers. |
課程要求 |
無 |
預期每週課後學習時數 |
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Office Hours |
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參考書目 |
1. Chasin M and Langer R: Biodegradable Polymers as Drug Delivery Systems.
Marcel Dekker, 1990, New York.
2. Hollinger JO: Biomedical Applications of Synthetic Biodegradable Polymers.
CRC Press, 1995, Boca Raton.
3. Lanza RP, Langer R and Vacanti J: Principles of Tissue Engineering.
Academic Press, 2000, San Diego.
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指定閱讀 |
無 |
評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
第1週 |
3/01 |
Biodegradable materials- Introduction
核心能力:1、2、7 |
第2週 |
3/08 |
Biodegradable Polymers for the Environment
核心能力:2、4、6 |
第3週 |
3/15 |
Biodegradable materials for medical applications
核心能力:3、5、7 |
第4週 |
3/22 |
Biodegradable Polymers for Drug Delivery
核心能力:1、4、7 |
第5週 |
3/29 |
BioPolymers-Collagen
核心能力:3、4、5
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第6週 |
4/05 |
Spring break 溫書假 |
第7週 |
4/12 |
BioPolymers-Gelatin
核心能力:2、3、5 |
第8週 |
4/19 |
BioPolymers-Chitin, Chitosan
核心能力:4、5、6 |
第9週 |
4/26 |
BioPolymers-Hyaluronic Acid and its Derivatives
核心能力:3、4、7 |
第10週 |
5/03 |
Mid-Term Quiz
核心能力:1、4、6 |
第11週 |
5/10 |
Polyhydroxyalkanoates (PHAs)
核心能力:2、4、5 |
第12週 |
5/17 |
Poly(alpha-hydroxy acids): PLA, PGA
核心能力:3、4、7 |
第13週 |
5/24 |
Ch 10 Polyanhydride
核心能力:1、5、6 |
第14週 |
5/31 |
Preparing Oral Term-paper Presentation
核心能力:1、3、6 |
第15週 |
6/07 |
Oral Term-paper Presentation
核心能力:2、4、7 |
第16週 |
6/14 |
Oral Term-paper Presentation
核心能力:2、4、7 |
第17週 |
6/21 |
Liposomes
核心能力:3、4、6 |
第18週 |
6/28 |
期末考
核心能力:1、4、6 |
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