課程資訊
課程名稱
分解性生醫材料
Degradable Biomaterials 
開課學期
101-2 
授課對象
工學院  醫學工程學研究所  
授課教師
黃義侑 
課號
Biomed7015 
課程識別碼
548 M0310 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期四2,3,4(9:10~12:10) 
上課地點
 
備註
本課程中文授課,使用英文教科書。教室:基醫403。
總人數上限:50人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1012Biomed7015 
課程簡介影片
 
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課程概述

一、課程簡介: 學分數:3 學分
Biodegradable (and/or bioabsorbable) biomaterials are widely used in sutures, bone plates, guiding of growth of tissues, drug delivery systems and other types of prostheses. In drug delivery systems, such polymers offer the great advantage of enabling site-specific or systemic administration of pharmaceutical agents without the need for subsequent retrieval of the delivery system. This course will provide a board spectrum of biodegradable polymers, ranging from synthesis, characterization, manufacturing… to medical applications. It will be useful to students who are new to the field and would like to understand more about the various properties and medical applications of biodegradable polymers.

課程內容:包括
 1. Introduction: Classification and mechanisms of biodegradation.
 2. Biodegradable polyesters: Lactide/glycolide polymers
 3. Biodegradable polyesters and tissue engineering
 4. Polyanhydrides
 5. Poly--Caprolactone and its copolymers
 6. Poly(ortho esters)
 7. Polyphosphazenes as new biomedical and bioactive materials
 8. Pseudopoly(amino acids)
 9. Natural biodegradable polymers: Albumin, collagen, and chitin/chitosan
10. Collagen and artificial skin
11. Liposome: Preparation and characterization
 12. Medical applications of liposomes: Drug delivery and gene therapy

二、先修課程:無

三、參考書目:
1. Chasin M and Langer R: Biodegradable Polymers as Drug Delivery Systems. Marcel Dekker, 1990, New York.
2. Hollinger JO: Biomedical Applications of Synthetic Biodegradable Polymers. CRC Press, 1995, Boca Raton
3. Lanza RP, Langer R and Vacanti J: Principles of Tissue Engineering. Academic Press, 2000, San Diego.
 

課程目標
This course will emphasize on the green plastcs, biodegradable macromolecules and polymers. That will be useful to students who are new to the field and would like to understand more about the various properties and medical applications of biodegradable polymers. 
課程要求
無 
預期每週課後學習時數
 
Office Hours
另約時間 
參考書目
1. Chasin M and Langer R: Biodegradable Polymers as Drug Delivery Systems.
Marcel Dekker, 1990, New York.
2. Hollinger JO: Biomedical Applications of Synthetic Biodegradable Polymers.
CRC Press, 1995, Boca Raton
3. Lanza RP, Langer R and Vacanti J: Principles of Tissue Engineering.
Academic Press, 2000, San Diego.
 
指定閱讀
無 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
期中考 
30% 
 
2. 
期末考 
30% 
 
3. 
期末報告 
30% 
 
4. 
上課出缺席 
10% 
 
 
課程進度
週次
日期
單元主題
第1週
2/21  Biodegradable Biomaterials(核心能力二,四)  
第2週
2/28  Biodegradable Biomaterials in medicine(核心能力二,四)  
第3週
3/07  collagen(核心能力二,四)  
第4週
3/14  collagen II(核心能力二,四)  
第5週
3/21  gelatin(核心能力二,四)  
第6週
3/28  chitosan(核心能力二,四)  
第7週
4/04  alginate(核心能力二,四)  
第8週
4/11  POLYHYDROXYALKANOATE (核心能力二,四)  
第9週
4/18  期中考  
第10週
4/25  PGLA PLA I(核心能力二,四)  
第11週
5/02  PGLA PLA II (核心能力二,四)  
第12週
5/09  Polyanhydride (核心能力四)  
第13週
5/16  PCL, FDA Tissue Glue (核心能力二,四) 
第14週
5/23  FDA Tissue Glue,Scaffold Processing(核心能力二,四) 
第15週
5/30  期末報告 
第16週
6/06  期末報告 
第17週
6/13  期末報告