課程大綱

課程資訊

課程名稱

生醫物理
Physics for Medicine and Biology

開課學期

100-2

授課對象

工學院醫學工程學研究所

授課教師

林文澧

課號

Biomed7052

課程識別碼

548 M0870

班次

學分

全/半年

半年

必/選修

選修

上課時間

星期五6,7,8(13:20~16:20)

上課地點

備註

本課程中文授課,使用英文教科書。教室：基醫503。
總人數上限：30人

Ceiba 課程網頁

http://ceiba.ntu.edu.tw/1002Biomed7052

課程簡介影片

核心能力關聯

核心能力與課程規劃關聯圖

課程大綱

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課程概述

1.Biomechanics： Equilibrium, forces on hip, stress and strain, hydrostatics, viscosity and viscous flow, etc.
2.Exponential growth and decay：Exponential growth and decay
3.System of many particles：Microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, Gibbs free energy, etc.
4.Transport in an infinite medium：Flux, continuity, solvent drag, diffusion, etc.
5.Transport through neutral membranes：Membrane, osmotic press, solute transport, artificial kidney, etc.
6.Impulses in nerve and muscle cell：Properties of nerves, electric field, charge distribution, leakage current, nerve impulse, electrotonus, Hodgkin-Huxley model, propagation, etc.
7.The exterior potential and the electrocardiogram：The exterior potential and the electrocardiogram
8.Biomagnetism：Biomagnetism
9.Electricity and magnetism at the cellular level：Electricity and magnetism at the cellular level
10.Biofeedback：Biofeedback

持續改善：因應每屆修課學生背景不同而調整授課內容或難易度

課程目標

以微觀的觀點探討生物的一些物理特性

改進：內容調整、新增測驗

課程要求

考試30& topic 3-7
期未報告：
一人交一份期未報告
於期未前兩週公佈相關題目
依題目要求尋找三至五篇相關paper
整理成一份書面報告及簡報檔
並於學期未上台做十五~二十分鐘的內容報告。

預期每週課後學習時數

Office Hours

另約時間

指定閱讀

無

參考書目

1.Intermediate Physics for Medicine and Biology, 3rd Edition, Hobbie RK, AIP Press, 1997.
2.The physical basis of Biochemistry: The Foundations of Molecular Biophysics, Bergethon PR, Springer-Verlag, 1998.

評量方式
(僅供參考)

No.	項目	百分比	說明
1.	期末報告	50%
2.	期中考	50%

課程進度

週次	日期	單元主題
第1週	2012/02/24	Introduction to the class [核心能力：2、4]
第2週	2012/03/02	3. System of many particles: Microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, Gibbs free energy. [核心能力：2、4]
第3週	2012/03/09	3. System of many particles: Microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, Gibbs free energy. [核心能力：2、4]
第4週	2012/03/16	3. System of many particles: Microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, Gibbs free energy. [核心能力：2、4]
第5週	2012/03/23	3. System of many particles: Microstates and macrostates, energy of a system, thermal equilibrium, entropy, Boltzmann factor, Nernst equation, chemical potential, Gibbs free energy. 4.Transport in an infinite medium: Flux, continuity, solvent drag, diffusion, etc. [核心能力：2、4]
第6週	2012/03/30	4.Transport in an infinite medium: Flux, continuity, solvent drag, diffusion, etc. [核心能力：2、4]
第7週	2012/04/06	清明節連假
第8週	2012/04/13	老師出國開會暫停一次
第9週	2012/04/20	4.Transport in an infinite medium: Flux, continuity, solvent drag, diffusion, etc 5.Transport through neutral membranes: Membrane, osmotic pressure, solute transport, artificial kidney, etc. [核心能力：2、4]
第10週	2012/04/27	5.Transport through neutral membranes: Membrane, osmotic pressure, solute transport, artificial kidney, etc. [核心能力：2、4]
第11週	2012/05/04	5.Transport through neutral membranes: Membrane, osmotic pressure, solute transport, artificial kidney, etc. 6.Impulses in nerve and muscle cells: Properties of nerves, electric field, charge distribution, leak current, nerve impulse, electrotonus, Hodgkin-Huxleymodel, propagation, etc. [核心能力：2、4]
第12週	2012/05/11	6. Impulse in nerve and muscle cells: Properties of nerves, electric field, charge distribution, leakage current, nerve impulse, electrotonus, Hodgkin-Huxley model, propagation, etc. [核心能力：2、4]
第13週	2012/05/18	6. Impulse in nerve and muscle cells: Properties of nerves, electric field, charge distribution, leakage current, nerve impulse, electrotonus, Hodgkin-Huxley model, propagation, etc. 7. Exterior potential and Electrocardiogram(ECG): Potential outside an axon, exterior potential for a pulse, ECG, electrical stimulation, electroencephalogram(EEG) [核心能力：2、4]
第14週	2012/05/25	Midterm Exam
第15週	2012/06/01	7.Exterior potential and Electrocardiogram(ECG): Potential outside an axon, exterior potential for a pulse, ECG, electrical stimulation, electroencephalogram(EEG) 8.Biomagnetism: Magnetic field around an axon, magnetocardiogram(MCG), magnetoencephalogram(MEG), magnetic stimulation, etc. [核心能力：2、4]
第16週	2012/06/08	8. Biomagnetism: Magnetic field around an axon, magnetocardiogram(MCG), magnetoencephalogram(MEG), magnetic stimulation, etc. 9. Electricity and magnetism at the cellular level: Donnan equilibrium, ion movement in solution, membrane channels, sensory transducers, etc. [核心能力：2、4]
第17週	2012/06/15	教授出國，暫停一次。
第18週	2012/06/22	期末報告一 [核心能力：2、4]
第19-1週	2012/06/25	期末報告二 [核心能力：2、4]
第19-2週	2012/06/26	期末報告三、期末問卷 [核心能力：2、4]