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課程名稱 |
分子遺傳學
MOLECULAR GENETICS |
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開課學期 |
98-2 |
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授課對象 |
生物資源暨農學院 農藝學系 |
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授課教師 |
林彥蓉 |
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課號 |
Agron5075 |
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課程識別碼 |
621 U5300 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
必修 |
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上課時間 |
星期一5,6(12:20~14:10)星期三5(12:20~13:10) |
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上課地點 |
農藝112農藝112 |
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備註 |
第二,三群選擇必修。與張俊哲合開
總人數上限：60人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/982mol_genetics |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
Molecular Genetics is the modern form of Genetics that studies the structure and function of genes at a molecular level. This field includes how genetic information is organized, replicated, expressed, regulated, and transferred from generation to generation. Topics of this course cover important issues from genes to genome and from proteins to proteome (details please see contents in the Syllabus). Concepts and applications of genome analysis and systems biology are also included. |
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課程目標 |
1. The Structure of DNA, and Genome Organization
2. Maintance of the Genome
3. Expression and regulation of Genes
4. Tools in Molecular Genetics
5. Integration of Molecular Genetics in Genome Science |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
I. Allison LA “Fundamental Molecular Biology”Blackwell Publishing. 2007 (合記)
II. Lewin B “GENES X”, Jones and Bartlett Publisher. 2010 (合記)
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參考書目 |
I. Watson JD, Baker TA, Bell SP, Gann A, Levin M, and Losick R. (2008) Molecular Biology of the Gene 6th edition. Cold Spring Harbor Laboratory Press. （偉明）
II. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Peter Walter. (2002) Molecular Biology of the Cell 4th edition. Garland Science.
注意：NCBI 已免費提供第四版 (4th edition)下載服務 (http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mboc4); 第五版已於 2009 年出版，不過還未上線。
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評量方式
(僅供參考) |
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No. |
項目 |
百分比 |
說明 |
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1. |
midterm I |
30% |
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2. |
midterm II |
35% |
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3. |
final |
35% |
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週次 |
日期 |
單元主題 |
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第1週 |
2/22,2/24 |
Introduction to Molecular Genetics |
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第2週 |
3/01,3/03 |
The Structure of DNA, and Genome Organization |
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第3週 |
3/08,3/10 |
DNA replication |
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第4週 |
3/15,3/17 |
DNA repair and recombination |
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第5週 |
3/22,3/24 |
From Gene to Protein |
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第6週 |
3/29,3/31 |
Midterm I |
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第7週 |
4/05,4/07 |
清明節，放假一天 |
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第8週 |
4/12,4/14 |
Transcription in prokaryotes |
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第9週 |
4/19,4/21 |
Transcription in eukaryotes |
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第10週 |
4/26,4/28 |
RNA processing |
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第11週 |
5/03,5/05 |
The Mechanism of Translation |
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第12週 |
5/10,5/12 |
Gene Regulation in Development |
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第13週 |
5/17,5/19 |
Midterm II |
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第14週 |
5/24,5/26 |
Integration of Molecular Genetics Tools |
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第15週 |
5/31,6/02 |
Transgenic Plant |
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第16週 |
6/07,6/09 |
Transposable Elements, Retroposons |
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第17週 |
6/14,6/16 |
Genome Analysis and Systems Biology |
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第18週 |
6-21 |
Final |
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