課程資訊
課程名稱
生態毒物模擬特論一
SPECIAL TOPICS ON ECOTOXICOLOGY MODELING(I) 
開課學期
96-2 
授課對象
生物資源暨農學院  生物環境系統工程學研究所  
授課教師
廖中明 
課號
BSE8019 
課程識別碼
622 D0470 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期一2,3,4(9:10~12:10) 
上課地點
農工金城 
備註
總人數上限:25人 
 
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課程概述

1. Freshwater Bivalve Ecotoxicology
􀁺 Detection of waterborne arsenic concentrations by a valve circadian subsystem in the freshwater clam Corbicula fluminea
􀁺 Acute toxicity and bioaccumulation of freshwater clam Corbicula fluminea exposed to arsenic
􀁺 Predicting bioavailability and bioaccumulation of arsenic by a valve circadian subsystem in the freshwater clam
2. Nanotoxicology
􀁺 Assessment of human exposure to nanomaterials
􀁺 Airborne ultrafine particles characterized by oxidative stress-induced DNA damage
􀁺 Risk-based approach on nanomaterials: Modeling, dosing, and health effects
3. Physiologically Based Pharmacokinetics (PBPK) in Risk Assessment
􀁺 Arsenic-related skin lesions risk posed to children from rice (Oryza sativa) consumption in West Bengal, India
􀁺 Airborne PM-bound arsenic exposure risk 

課程目標
1. Freshwater Bivalve Ecotoxicology
􀁺 Detection of waterborne arsenic concentrations by a valve circadian subsystem in the freshwater clam Corbicula fluminea
􀁺 Acute toxicity and bioaccumulation of freshwater clam Corbicula fluminea exposed to arsenic
􀁺 Predicting bioavailability and bioaccumulation of arsenic by a valve circadian subsystem in the freshwater clam
2. Nanotoxicology
􀁺 Assessment of human exposure to nanomaterials
􀁺 Airborne ultrafine particles characterized by oxidative stress-induced DNA damage
􀁺 Risk-based approach on nanomaterials: Modeling, dosing, and health effects
3. Physiologically Based Pharmacokinetics (PBPK) in Risk Assessment
􀁺 Arsenic-related skin lesions risk posed to children from rice (Oryza sativa) consumption in West Bengal, India
􀁺 Airborne PM-bound arsenic exposure risk 
課程要求
Mid-term and Final Reports
Class Presentation 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
Farris JL, van Hassel JH. 2007. Freshwater Bivalve Ecotoxicology. CRC Press, New York, NY.
Monteiro-Riviere NA, Tran CL. 2007. Nanotoxicology. Informa, New York NY.
Reddy MA et al. 2005. Physiologically Based Pharmacokinetic Modeling. Wiley, New York, NY. 
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