課程資訊
課程名稱
細胞學特論
Current topics in cell biology 
開課學期
100-2 
授課對象
生物資源暨農學院  農業化學研究所  
授課教師
羅凱尹 
課號
AC5081 
課程識別碼
623EU4480 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期三A(18:25~19:15) 
上課地點
農化二B10 
備註
本課程以英語授課。與德州大學奧斯丁分校Arlen Johnson教授合授,第一節必到,規定詳課綱
總人數上限:50人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1002ctcb 
課程簡介影片
 
核心能力關聯
核心能力與課程規劃關聯圖
課程大綱
為確保您我的權利,請尊重智慧財產權及不得非法影印
課程概述

This course will cover the mechanisms of nucleocytoplasmic transport in eukaryotic cells. The nuclear pore complex of the nuclear envelope provides a selective barrier for macromoleculaes in a eukaryotic cell. Essentially all proteins found in the nucleus are transported into the nucleus in a directed fashion. In addition, all cytoplasmic RNAs, including mRNA, miRNAs, rRNA (as ribosomes) and tRNAs are exported in a highly regulated fashion. Most of these transport events are directed by a family of related proteins called karyopherins. These transport receptors promote transport through the highly hydrophobic channel of the nuclear pore complex. Remarkably, the mechanism of transport does not require energy. However, ATPases and GTPases provide directionality to the transport pathways. Finally, recent atomic structures are beginning to shed light on the molecular mechanisms that govern transport. 

課程目標
To get insights on the mechanisms of nucleocytoplasmic transport and the significance of physiology 
課程要求
上課時間:2/22; 2/29; 3/1; 3/2; 3/6; 3/7; 3/8晚上,6:30-9:00,不可缺席

Need to finish “Molecular Biology” course
Class discussion will be highly encouraged.
 
預期每週課後學習時數
 
Office Hours
 
參考書目
(1) B. Alberts, A. Johnson, J. Lewis, M. Raff, K. Roberts, P. Walter. 2002. Molecular biology of the cell. Garland Science. New York. USA
(2) Handouts provided by instructors
 
指定閱讀
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第8週
3/25  Take-home exam