|
週次 |
日期 |
單元主題 |
|
第1週 |
9/03; 9/04 |
• Course Introduction
• DNA discovery: history and ideas |
|
第2週 |
9/10; 9/11 |
• Transforming Principle - why?
• Blender Experiment
• DNA structure
• DNA chemistry |
|
第3週 |
9/17; 9/18 |
• DNA denaturation, renaturation, and hybridization
• DNA, genes, genome, chromatin, and chromosome
• Genome organization
• DNA and your daily life |
|
第4週 |
9/24; 9/25 |
• Genome organization
• Centrioles, centrosome, and sister-chromatid seperation
• The RNA World
• Demonstration of DNA's semi-conservative replication
• Music and molecular biology |
|
第5週 |
10/01; 10/02 |
• DNA Replication (I)
• DNA Replication (II) |
|
第6週 |
10/08; 10/09 |
• DNA Replication (III) |
|
第7週 |
10/15; 10/16 |
• DNA Replication (IV)
• DNA Replication -- final part
• Telomere and telomerase |
|
第8週 |
10/22; 10/23 |
mid-term exam: open-book exam
• Telomere and telomerase -- final part
• DNA sequencing
• Transcription — from a whole-genome point of view |
|
第9週 |
10/29; 10/30 |
• Transcription — basic principles |
|
第10週 |
11/05; 11/06 |
• Yeast as a model organism for studying molecular genetics
• Splicing (I)
• Splicing (II) |
|
第11週 |
11/12; 11/13 |
• Molecular basis of eukaryotic transcription
• Molecular basis of translation |
|
第12週 |
11/19; 11/20 |
• Molecular basis of translation -- part II
• Molecular basis of translation -- part III |
|
第13週 |
11/26; 11/27 |
• Molecular basis of translation -- part IV
• Gene regulation — part I
• C. elegans as a model organism |
|
第14週 |
12/03; 12/04 |
• Gene regulation —— the dual control of lac operon
• Fruit fly and mosquito as a molecular model |
|
第15週 |
12/10; 12/11 |
• Gene Regulation
• Zebrafish as a molecular model
• Gene regulation —— writing and reading the histone codes
• RNAi |
|
第16週 |
12/17; 12/18 |
written exam -- 12/17 or 12/18 |