|
週次 |
日期 |
單元主題 |
|
第1週 |
|
• Course Introduction
• DNA discovery: history and ideas |
|
第2週 |
|
• Transforming Principle - why?
• Blender Experiment
• DNA structure
• DNA chemistry |
|
第3週 |
|
• DNA denaturation, renaturation, and hybridization
• DNA, genes, genome, chromatin, and chromosome
• Genome organization
• DNA and your daily life |
|
第4週 |
|
• Genome organization
• Centrioles, centrosome, and sister-chromatid seperation
• The RNA World
• Demonstration of DNA's semi-conservative replication
• Music and molecular biology |
|
第5週 |
|
• DNA Replication (I)
• DNA Replication (II) |
|
第6週 |
|
• DNA Replication (III) |
|
第7週 |
|
• DNA Replication (IV)
• DNA Replication -- final part
• Telomere and telomerase |
|
第8週 |
|
10/23: mid-term exam
• Telomere and telomerase -- final part
• DNA sequencing
• Transcription — from a whole-genome point of view |
|
第9週 |
|
• Transcription — basic principles |
|
第10週 |
|
• Yeast as a model organism for studying molecular genetics
• Splicing (I)
• Splicing (II) |
|
第11週 |
|
• Molecular basis of eukaryotic transcription
• Molecular basis of translation |
|
第12週 |
|
• Molecular basis of translation -- part II
• Molecular basis of translation -- part III |
|
第13週 |
|
• Molecular basis of translation -- part IV
• Gene regulation — part I
• Molecular Biology: C. elegans as a model organism |
|
第14週 |
|
• Gene regulation —— the dual control of lac operon
• Epigenetic Regulatory Mechanisms & Phenomenons |
|
第15週 |
|
• Gene Regulation
• Zebrafish development
• Gene regulation —— writing and reading the histone codes
• RNAi |
|
第16週 |
|
written exam |