課程資訊
課程名稱
後生遺傳學
Epigenetics 
開課學期
101-1 
授課對象
生物資源暨農學院  生物科技研究所  
授課教師
林劭品 
課號
Biot8001 
課程識別碼
642ED0020 
班次
 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一5,6,7(12:20~15:10) 
上課地點
生技所415 
備註
本課程以英語授課。與林詩舜合開
限博士班
總人數上限:20人
外系人數限制:15人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1011Epigenetics 
課程簡介影片
 
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課程概述

Introduction–Epigenetic Overview
DNA methylation and genome defense
RNAi and heterochromatin
Evolution of mammalian epigenetic control systems
Epigenetics and development
Epigentics and human disease
X-inactivation
Genomic imprinting in mammals
Genomic imprinting in plants
Epignetics and reprogramming
Epigenetics in assisted reproductive techniques
Applied epigenetics: flowering plants and tissue engineering
 

課程目標
Course description: This graduate course aims to introduce basic epigenetic concepts and research techniques available to address epigenetic questions in mammals as well as other organisms. Students are expected to develop the ability to critically evaluating and interpreting published research articles. They will also learn to extract information from international conferences by listening to experts of each field introducing their research (as in the CD-ROM). 
課程要求
 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
Week 1
09/10  (SP Lin) Epigenetics Overview 
Week 2
9/17  Conserved battle between transposable elements and germ cells

 
Week 3
9/24  Epigentic in plants (miRNA) (SS Lin)
Preparation for the leaded discussion (SP Lin) 
Week 4
10/01  Epigentic in plants (tasiRNA) (SS Lin) 
Week 5
10/08  Commonly used techniques in Epigenetic studies
SP Lin: Leaded discussion session (I) 
Week 6
10/15  (SS Lin): long non-coding RNA
 
Week 7
10/22  SP Lin/ SS Lin: Leaded discussion session  
Week 8
10/29  SP Lin: Summary and Leaded discussion session
 
Week 9
11/05  11/5 Open Book Midterm Exam
11/6 (Tuesday) Guest speaker: Prof. 劉怡均 
Week 10
11/12  (SP Lin)Genomic imprinting and X-inactivation in mammals; Discussion of the mid-term exam paper 
Week 11
11/19  (SS Lin): DNA methylation in plant 
Week 12
11/26  (SS Lin): Imprinting in plants 
Week 13
12/03  (SS Lin) Leaded discussion 
Week 14
12/10  (SP Lin) Epigenetics in Developments and Diseases 
Week 15
12/17  (SP Lin): Nutrition, neuron and reprogramming 
Week 16
12/24  Students' show time
piRNAs Initiate an Epigenetic Memory of Nonself RNA in the C. elegans
Germline 
Week 17
12/31  12/22 Students' show time
The PIWI protein acts as a predictive marker for human.pdf 
Week 18
1/7  Minireview/Preview/News and Views/Reviewer's comments Final report due