課程名稱 |
進階動物生物技術 Advanced Animal Biotechnology |
開課學期 |
101-1 |
授課對象 |
生物資源暨農學院 生物科技研究所 |
授課教師 |
宋麗英 |
課號 |
Biot5007 |
課程識別碼 |
642EU0100 |
班次 |
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學分 |
3 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期三2,3,4(9:10~12:10) |
上課地點 |
生技所415 |
備註 |
本課程以英語授課。 限學士班三年級以上 總人數上限:20人 外系人數限制:15人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1011adv_anim_biotech |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
The objectives of this course are 1) to provide graduate students with an overview of recent developments in animal biotechnology; 2) to improve graduate students' presentation skills. After extensive review and discussion of various biotechnologies, each student will be asked to give a presentation in the area other than their own research. I will meet with all students individually several times during their literature search, preparation of presentation outline and presentation practice. Lab demonstrations of basic embryology techniques will be included as well. Guest speakers will plan to invite for the lectures as necessary. |
課程目標 |
1. Introduction and overview of animal biotechnology
2. Folliculogenesis, oogenesis, embryogenesis
3. In vitro maturation/fertilization and embryo culture — state of the art
4. Embryo cryopreservation
5. Genetic micromanipulations of embryos
6. DNA identifications of transgenetic
7. Transgenic animals as organ donors (xenotransplantation)
8. Human Assisted Reproductive Technology (ART)
9. Sperm and embryo sexing
10. Somatic cell nuclear transfer- state of the art
11. Telomere, telomerase and gene reprogramming in age of cloned animal
12. X chromosome inactivation
13. Genetic imprinting
14. Functional genomics in humans and animals-state of the art
15. Introduction of embryonic stem cells
16. Introduction of adult stem cells
17. Therapeutic cloning— state of the art |
課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
1. Developmental Biology, eighth edition, Scott F. Gibert, Sinauer Associates, Inc., USA
2. Reproduction in Farm Animals, seventh edition, E.S.E.Hafez and B. Hafez, Lippincott Williams and Wilkins
3. Pathways to pregnancy and parturition, second edition, P.L. Senger, Current Conceptions, Inc. USA
4. PubMed, www.pubmed.gov |
評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
第1週 |
9/12 |
Introduction and overview of animal biotechnology |
第2週 |
9/19 |
In vitro maturation/ fertilization and embryo culture - state of the art |
第3週 |
9/26 |
Oocyte and embryo cryopreservation |
第4週 |
10/03 |
Sperm and embryo sexing - state of the art |
第5週 |
10/10 |
National Day |
第6週 |
10/17 |
Human IVF/ART, genetic diagnosis (PGD) |
第7週 |
10/24 |
Nuclear reprogramming by somatic cell nuclear transfer |
第8週 |
10/31 |
Gene targeting using somatic cell nuclear transfer in farm animals |
第9週 |
11/07 |
Telomere, telomerase and gene reprogramming in age cloned animal |
第10週 |
11/14 |
Epigenetic reprogramming in cloned embryos |
第11週 |
11/21 |
Student presentation – |
第12週 |
11/28 |
Student presentation – |
第13週 |
12/05 |
Exam_
Multichoice and essay questions |
第14週 |
12/12 |
Embryonic stem cells |
第15週 |
12/19 |
Adult stem cells |
第16週 |
12/26 |
Nuclear reprogramming by induced pluripoent stem cells |
第17週 |
1/02 |
Student presentation –
Final report |
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