課程名稱 |
配子與幹細胞之上位遺傳學 GENETICS AND EPIGENETICS IN GERM AND STEM CELLS |
開課學期 |
98-2 |
授課對象 |
生物資源暨農學院 生物科技研究所 |
授課教師 |
林劭品 |
課號 |
Biot5005 |
課程識別碼 |
642EU0070 |
班次 |
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學分 |
2 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期三5,6(12:20~14:10) |
上課地點 |
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備註 |
本課程以英語授課。上課地點,本所R410 限學士班三年級以上 總人數上限:30人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/982EpiGermStem |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
Depends on the background of the students, 1/2 to 2/3 of the lectures will be given by the instructor for introducing basic concepts in Gametogenesis, Stem cells and the regulation by Genetics and Epigenetics. For the rest of the classes, students will be assigned the most updated original research papers as well as the milestone publications. They will be randomly divided into 2 groups for each assignment. One group will be presenting the articles and students in the other group are expected to challenge the papers from the experimental design, the methodology to the interpretation of the data. Students in the 1st group should defend for the papers as if it’s their manuscript. Students from the 2nd group should also provide constructive advice as how to improve the manuscript so that it can be published in a higher impact journal. |
課程目標 |
On top of learning the basic concepts of gametogenesis, epigenetics and reprogramming, students are expected to develop the ability to critically evaluate and interpret published research articles. In addition, they will learn the art of reviewing as well as defending a manuscript for publication. |
課程要求 |
Preferably having backgrounds in one of the following subjects: Biochemistry, Cell Biology, Genetics, Molecular Biology or Epigenetics |
預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
Updated journal articles and reviews; “Epigenetics: Concepts, Theories, Paradigms and Mechanisms” and “Stem cell and Regenerative Medicine” CD-Roms (A Henry StewartTalks Series in the Life Sciences) |
評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
第1週 |
2/24 |
Introduction (Stem cell and Epigenetics) |
第2週 |
3/03 |
Introduction (Germ cell and Epigenetics) |
第3週 |
3/10 |
Epigenetic Regulations Mechanisms |
第4週 |
3/17 |
Genomic Imprinting |
第5週 |
3/24 |
Transgenerational Reprogramming |
第6週 |
3/31 |
X. Y chromosome in germ cell development and male infertility(蕭百忍老師) |
第7週 |
4/07 |
Exam preparation break |
第8週 |
4/14 |
Important concepts in stem cell research(郭紘志老師) |
第9週 |
4/21 |
Mid-term exam |
第10週 |
4/28 |
Disscussion of midterm exam |
第11週 |
5/05 |
SCNT and iPS cells(宋麗英老師) |
第12週 |
5/12 |
High throughput sequence(林詩舜老師) |
第13週 |
5/19 |
Epigenetics in stem cell differentiaion |
第14週 |
5/26 |
Technology |
第15週 |
6/02 |
Final discussion-1 |
第16週 |
6/09 |
Final discussion-2 |
第17週 |
6/16 |
Dragon Boat Festival (Holiday) |
第18週 |
6/23 |
Final discussion-3 |
第19週 |
6/30 |
Final examinations |
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