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課程名稱 |
磁共振影像原理及應用
Magnetic Resonance Imaging: Principles and Its Applications |
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開課學期 |
103-1 |
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授課對象 |
電機資訊學院 電機工程學研究所 |
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授課教師 |
鍾孝文 |
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課號 |
EE5062 |
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課程識別碼 |
921 U2930 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期四6,7,8(13:20~16:20) |
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上課地點 |
明達203 |
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備註 |
總人數上限：24人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1031EE5062_MRI14 |
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課程簡介影片 |
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核心能力關聯 |
本課程尚未建立核心能力關連 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
核磁共振信號源
激發與偵測
弛緩效應、自旋迴訊
空間編碼與影像形成
儀器硬體：主磁體、梯度線圈、射頻線圈
影像品質與對比
k 空間原理、面迴訊影像
假影與消除方式
快速掃瞄
流體效應與血管攝影
相位對比流速分析、擴散影像
微灌流影像、腦功能影像
臨床神經頻譜、化學位移影像
生物效應與安全性 |
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課程目標 |
提供磁振造影基礎知識。課程方向偏重工程技術與臨床醫學之跨領域結合。 |
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課程要求 |
預修科目：信號與系統，以及電磁學、計算機、電路、傅立葉轉換、數位影像處理、量子物理等方面之基本觀念。
評量方式：作業 40%、期中考30%（含 20% 筆試與 10% 實驗室考試）、期末考 30%。
作業一律於下次上課繳交，遲交一律不收。 |
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預期每週課後學習時數 |
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Office Hours |
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參考書目 |
教科書： 課堂講義、指定閱讀論文等。
For rich students, the "MRI teaching software" (package of 7 individual modules) CD-ROM (running on Macintosh II and above) from the University of Pennsylvania should serve as a good introductory material. Contact Professor Felix W. Wehrli at 0021-215-662-7951 (Tel) or 0021-215-349-5925 (Fax) for price (~ US$ 550). Educational discount available upon request.
參考書目： S.C. Bushong "Magnetic resonance imaging: physical and biological principles" 2nd Ed., Mosby 1996 (台大醫圖): A nice and fun book for those who know almost nothing about MRI.
T.C. Farrar "Pulse nuclear magnetic resonance spectroscopy: an introduction to the theory and applications" Farragut 1989 (中研院生醫圖書館): Very good in illustrations of NMR principles and relaxation theories.
F.W. Wehrli, D. Shaw, J.B. Kneeland "Biomedical magnetic resonance imaging: principles, methodology, and applications" VCH 1988 (台大醫圖): Contains good chapters on principles, contrast, contrast agents, bioeffects, etc. Not all are excellent but probably worth buying as an entry-level reference.
E.M. Haacke et al. "Magnetic resonance imaging: Physical principles and sequence design" Wiley-Liss, 1999 (台大總圖與醫圖): Perhaps the first dedicated book on MRI written in the language of physicists and engineers with emphasis on image acquisition techniques. Pretty much up-to-date but perhaps difficult for entry-level students.
D.D. Stark, W.G. Bradley "Magnetic resonance imaging" 3rd Ed., Mosby, 1999 (台大醫圖. 總圖僅 2nd Ed. available): Three big volumes (two for 2nd Ed.) contain good reviews on many important topics in MRI. But in an edited book you know that quality control is difficult.
C.L. Partain et al. "Magnetic resonance imaging" 2nd Ed., Saunders, 1988 (台大總圖與醫圖): Same as #5 above, but is much older and contains very few chapters on newly developed techniques. Good on instrumentation chapters. |
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指定閱讀 |
待補 |
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/18 |
Introduction to course format; Introduction to MRI |
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第2週 |
9/25 |
NMR signals; Excitation & detection; Spin echo |
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第3週 |
10/02 |
Relaxation; Spatial encoding (slice selection) |
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第4週 |
10/09 |
Spatial encoding (freq & phase encoding) & image formation |
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第5週 |
10/16 |
Instrumentation: Magnets, gradient coils |
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第6週 |
10/23 |
Instrumentation: RF coils; Image quality & contrast |
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第7週 |
10/30 |
Principles of k-space and EPI |
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第8週 |
11/06 |
Artifacts & remedies |
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第9週 |
11/13 |
Mid-term written exam |
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第10週 |
11/20 |
Mid-term lab exam |
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第11週 |
11/27 |
Fast scanning MRI |
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第12週 |
12/04 |
Flow effects and MR angiography |
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第13週 |
12/11 |
Phase-contrast MRA and diffusion MRI |
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第14週 |
12/18 |
Perfusion MRI and BOLD brain functional imaging |
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第15週 |
12/25 |
Clinical neural spectroscopy and chemical shift imaging |
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第16週 |
1/01 |
開國紀念日放假 |
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第17週 |
1/08 |
Bioeffects & safety |
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