課程資訊
課程名稱
生醫分子影像導論
Fundamentals of Molecular Imaging 
開課學期
104-2 
授課對象
學程  神經生物與認知科學學程  
授課教師
陳志宏 
課號
EE5124 
課程識別碼
921 U7800 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期二2,3,4(9:10~12:10) 
上課地點
電二102 
備註
與顏若芳、忻凌偉、駱遠、陳中明、李百祺、莊曜宇合開
總人數上限:35人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1042EE5124_ 
課程簡介影片
 
核心能力關聯
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課程大綱
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課程概述

Molecular imaging is the technology that successfully combined molecular biology and clinical medicine, and it will be one of potential fields of medicine in the future. Generally, there are three advantages on molecular imaging research: first, it can transform complicated processes of gene expression and signal transduction into image visually, and that one can realize the possible disease mechanism and features; second, it's able to find early on molecular variations of disease and the process of pathology; last, it can in vivo observe continuously the mechanism and effect on drug or gene therapy. Molecular imaging integrated molecular biochemistry, data processing, nanotechnology and imaging processing, and then it possesses the properties of high specificity, high sensitivity and ultra-high spatial resolution.

Introduction 2 weeks
Molecular Biology 3 weeks
(Prof. Eroc Chung, and Prof. Fu-Hsiung Chang)
Optical Molecular Imaging 3 weeks
(Prof. Chi-Kuang Sun)
MR Molecular Imaging 2 weeks
(Prof. Jyh-Horng Chen)
Ultrasonic Molecular Imaging 2 weeks
(Prof. Pai-Chi Li)
The Contrast agent for Molecular Imaging 2 weeks
? The property of contrast agent
? The design and synthesis of the contrast agent

The Applications of Molecular Imaging 2 weeks
 

課程目標
課程要求
1.Grade
Homework 40%
Midterm Exam 20%
Final project report 20%
Final Exam 20%

2.Prerequisites (recommended but not required)
Fundamental modern physics, General chemistry, Organic chemistry, General biology, Molecular biology 
預期每週課後學習時數
 
Office Hours
 
參考書目
TEXTBOOK: THERE IS NOT A SINGLE UP-TO-DATE QUANTITATIVE BOOK CONTAINING MOST OF THE MATERIALS IN THIS COURSE, BUT SEVERAL REFERENCE BOOKS ARE RECOMMENDED IN APPENDIX I. 
指定閱讀
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
2/23  Fundamentals of Medical Imaging
課程大綱 
第2週
3/01  Introduction to molecular Imaging 
第3週
3/08  Fundamentals of Molecular Biology (1) 
第4週
3/15  Fundamentals of Molecular Biology (2) 
第5週
3/22  Fundamentals of Molecular Biology (3) 
第6週
3/29  Molecular Imaging of Probe Design 
第7週
4/05  例假日補假 
第8週
4/12  The Application of Molecular Imaging-Molecular Imaging of Nuclear Medicine 
第9週
4/19  Mid Term Exam (20%) 
第10週
4/26  MR Fundamentals/ MR Molecular Imaging (1) 
第11週
5/03  MR Molecular Imaging (2) 
第12週
5/10  Optical Molecular Imaging (1):(a) Introduction of phase contrast microscopy/confocal/super-resolution, and (b) review of its related applications 
第13週
5/17  Ultrasonic Molecular Imaging (1) 
第14週
5/24  Ultrasonic Molecular Imaging (2) Photo acoustic Molecular Imaging 
第15週
5/31  Optical Molecular Imaging (2):Introduction of (a) light sheet microscopic imaging, and (b) optical tweezers for in vivo observation. 
第16週
6/07  Medical Imaging analysis 
第17週
6/14  Final Report 
第18週
6/21  Final Exam (20%)