課程名稱 |
發生生物學 Developmental Biology |
開課學期 |
110-1 |
授課對象 |
生命科學院 生命科學系 |
授課教師 |
李士傑 |
課號 |
LS4003 |
課程識別碼 |
B01 41010 |
班次 |
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學分 |
3.0 |
全/半年 |
半年 |
必/選修 |
必修 |
上課時間 |
星期五2,3,4(9:10~12:10) |
上課地點 |
生科419 |
備註 |
B群選擇必修。與丁照棣、郭典翰、蔡素宜合授 總人數上限:40人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1101LS4003_ |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
Developmental biology is one of the important fields in basic biology that has a profound impact on human health. It initiates from the morphological observation of chick embryo development to the unraveling of the molecular control of embryonic development in a variety of organisms. It is a miracle to learn how a single cell develops into a fully functional adult and we still do not know much about the underlying mechanisms for different processes during development. This course is designed to build the ground for students with an interest in developmental biology. We will discuss the basic principles and molecular controls of embryonic development. We will emphasize the progression from gametogenesis, fertilization, cleavage to gastrulation (i.e. the formation of the gut). We will also cover cell fate and embryonic axis determination. The popular experimental models used by current developmental biologists will also be examined in detail. We will go over the formation and derivatives from three germ layers, ectoderm, mesoderm and endoderm. Lastly, tissue and organ regeneration and the progression of regenerative medicine will be highlighted. |
課程目標 |
1. Learn the basic principles, processes, regulatory mechanisms during embryogenesis and later development.
2. Expose to contemporary research in developmental biology
3. Learn and practice scientific thinking |
課程要求 |
Students should have college-level General Biology. |
預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
Developmental Biology. 11/e
作者:Gilbert
年份:2016
出版社:SINAUER ASSOCIATES
書號:SI0181
ISBN:9781605354705 |
參考書目 |
Assigned papers or media |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
期中考 |
45% |
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2. |
期末考 |
45% |
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3. |
平時成績 |
10% |
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週次 |
日期 |
單元主題 |
第1週 |
09/24 |
History and principles in Developmental Biology (JL) |
第2週 |
10/01 |
Differential Gene Expression in Development (JL) |
第3週 |
10/08 |
Fertilization (JL) |
第4週 |
10/15 |
Early development: Vertebrates (JL) |
第5週 |
10/22 |
Early development & Axis Determination in Drosophila (CTT) |
第6週 |
10/29 |
Sex determination; CH17 Germ Line (CTT) |
第7週 |
11/05 |
Limb formation (CTT) |
第8週 |
11/12 |
Midterm (JL & CTT) |
第9週 |
11/19 |
Early development by stereotypic cell lineages (DHK) |
第10週 |
11/26 |
Developmental mechanisms of evolutionary change (DHK) |
第11週 |
12/03 |
Emergence of ectoderm (DHK) |
第12週 |
12/10 |
Neural crest (DHK) |
第13週 |
12/17 |
Paraxial and Intermediate Mesoderm (SYT) |
第14週 |
12/24 |
Lateral Plate Mesoderm and the Endoderm (SYT) |
第15週 |
12/31 |
Holiday (No Class) |
第16週 |
01/07 |
Pluripotency, Embryonic Stem cells and iPSC. Su-Yi Tsai (SYT) |
第17週 |
01/14 |
Final Examination (DHK & SYT) |
第18週 |
01/21 |
Flexible learning |
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