課程資訊
課程名稱
生物技術基礎與前瞻
Fundamentals and Frontiers of Biotechnology 
開課學期
102-2 
授課對象
生命科學院  生化科技學系  
授課教師
胡維碩 
課號
BST5041 
課程識別碼
B02 U1040 
班次
 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一3,4,@(10:20~) 
上課地點
 
備註
微生物與細胞科技領域。B11教室上課。實際上課時間請洽授課教師或看課程介紹。與楊健志、李昆達合開
總人數上限:27人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1022BST5041_FFB 
課程簡介影片
 
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課程概述

This course is designed for students with a science/engineering background to learn fundamentals of bioengineering and frontiers of biotechnology. This course begins from the topics regarding bioengineering: material balance in biological systems, rates and kinetics overview of bioreactors, continuous culture, and oxygen transfer in bioreactors. And then to the hottest topics in biotechnology in the latter half of the semester. These topics are: enzyme technology, recombinant proteins, metabolic engineering, genome and genomic technology, cell culture processes, synthetic biotechnology, and stem cell technology. Finally, students are grouped (2-3 persons/group) to prepare a presentation of their special project for summarization of what they have learned in this course. 

課程目標
The objective of the course is to provide students with a comprehensive and concise overview of engineering principles applying to biotechnological processes with an emphases on stoichiometric and kinetic analysis and quantitative synthesis of biological knowledge, and the recent developed key issues in biotechnology. 
課程要求
Students are expected to have had biochemistry or microbiology or cell biology, and concept of differential equations, or are at senior undergraduate or graduate levels. 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
Wei-Shou Hu, Cell culture bioprocess engineering (Wei-Shou Hu) 
參考書目
Textbook: Cell culture bioprocess engineering
Reference: Belter, P., Cussler, E.L. and Hu, W.-S., Bioseparations:
Downstream Processing for Biotechnology, 1988 (John Wiley and Sons)
Handouts will be provided. Selected articles will be assigned.
 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
2/17  Overview Of Biotechnology, Industrial Organisms, And Cells 
第2週
2/24  Stoichiometry and yields in biological systems 
第3週
3/03  Kinetics Of Cell Growth And Production 
第4週
3/10  Material Balance In Biological Systems 
第5週
3/17  Metabolic flux analysis 
第6週
3/24  Overview Of Bioreactors 
第7週
3/31  Continuous Culture 
第8週
4/07  Oxygen Transfer in Bioreactors 
第9週
4/14  Mid-Term Exam 
第10週
4/21  Biocatalysis-Enzyme Technology 
第11週
4/28  Cell Culture Processes 
第12週
5/05  Metabolic Engineering 
第13週
5/12  Genome and Genomic Technology 
第14週
5/19  Synthetic Biotechnology 
第15週
5/26  Stem cell technology 
第16週
6/02  端午節放假 
第17週
6/09  Project Presentation 
第18週
6/16  Final Exam