課程名稱 |
早期胚胎發生學 Early Developmental Embryology |
開課學期 |
113-1 |
授課對象 |
學程 幹細胞與再生醫學學程 |
授課教師 |
李士傑 |
課號 |
LS5019 |
課程識別碼 |
B21EU1320 |
班次 |
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學分 |
2.0 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期一3,4(10:20~12:10) |
上課地點 |
生科632 |
備註 |
本課程以英語授課。 限學士班三年級以上 總人數上限:15人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
Developmental biology is one of the important fields in basic biology that has a profound impact on human health. It initiates from the morphological observation of chick embryo development to the unraveling of the molecular control of embryonic development in a variety of organisms. It is a miracle to learn how a single cell develops into a fully functional adult and we still do not know much about the underlying mechanisms for different processes during development. We will discuss the basic principles and molecular controls of embryonic development. We will emphasize the progression from gametogenesis, fertilization, cleavage to gastrulation (i.e., the formation of the gut). We will also cover cell fate and embryonic axis determination. The popular experimental models used by current developmental biologists will also be examined in detail. We will go over the formation and derivatives from three germ layers, ectoderm, mesoderm and endoderm. Lastly, tissue and organ regeneration and the progression of regenerative medicine will be hi |
課程目標 |
Developmental biology is one of the important fields in basic biology that has a profound impact on human health. It initiates from the morphological observation of chick embryo development to the unraveling of the molecular control of embryonic development in a variety of organisms. It is a miracle to learn how a single cell develops into a fully functional adult and we still do not know much about the underlying mechanisms for different processes during development. We will discuss the basic principles and molecular controls of embryonic development. We will emphasize the progression from gametogenesis, fertilization, cleavage to gastrulation (i.e., the formation of the gut). We will also cover cell fate and embryonic axis determination. The popular experimental models used by current developmental biologists will also be examined in detail. We will go over the formation and derivatives from three germ layers, ectoderm, mesoderm and endoderm. Lastly, tissue and organ regeneration and the progression of regenerative medicine will be hi |
課程要求 |
Students should have college-level General Biology and Genetics. |
預期每週課後學習時數 |
4- to 6-hour study time is expected. |
Office Hours |
另約時間 備註: Students are welcome to make an appointment with the instructor by e-mails to discuss couse-related questions. |
指定閱讀 |
Rpinciles of Development (International 5th edition) Lewis Wolpert et al. |
參考書目 |
Developmental Biology by MJF Barresi and SF Gilbert (12/e, Sinauer Associates/ Oxford) ISBN 978-160535822
We have reserved a copy as a reference book for this course and students can read the textbook in the Library.
You can also get a Kindle Edition at Amazon. |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
Midterm |
30% |
Assay questions |
2. |
Oral Presentation |
30% |
15-30 min oral presentation in DB-related papers within 5 years. |
3. |
Report |
30% |
A report on the presented paper for 2-5 pages.
Format: a word file, single spaced, Time New Roman at a font size of 12. |
4. |
Class participation |
10% |
Class attendance & participation |
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週次 |
日期 |
單元主題 |
第1週 |
09/02/24 |
History and principles in Developmental Biology |
第2週 |
09/09/24 |
History and principles in Developmental Biology |
第3週 |
09/16/24 |
Fertilization (CH7) |
第4週 |
09/23/24 |
Cleavage & Gastrulation |
第5週 |
09/30/24 |
Body Axis Specification I |
第6週 |
10/07/24 |
Body Axis Specification II |
第7週 |
10/14/24 |
Germ layers I |
第8週 |
10/21/24 |
Germ layers II |
第9週 |
10/28/24 |
Gametogenesis |
第10週 |
11/04/24 |
Pluripotency, Embryonic Stem cells and iPSC. |
第11週 |
11/11/24 |
Midterm |
第12週 |
11/18/24 |
Student presentation I |
第13週 |
11/25/24 |
Student presentation II |
第14週 |
12/02/24 |
Student presentation III |
第15週 |
12/09/24 |
Student presentation IV |
第16週 |
12/16/24 |
Final week: Report Writing |