課程資訊
課程名稱
發育生物學與再生醫學經典及前瞻研究
Research in Developmental Biology and Regenerative Medicine 
開課學期
109-1 
授課對象
生命科學院  生命科學所  
授課教師
李士傑 
課號
LS5088 
課程識別碼
B21EU2370 
班次
 
學分
2.0 
全/半年
半年 
必/選修
選修 
上課時間
星期五9,10(16:30~18:20) 
上課地點
生科3C 
備註
本課程以英語授課。與丁照棣合授
總人數上限:50人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1091LS5088_ 
課程簡介影片
 
核心能力關聯
本課程尚未建立核心能力關連
課程大綱
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課程概述

This course will be based on the Nature “Milestone in Development” to introduce classical developmental biology (DB) studies and contemporary regenerative medicine (RM). It will be started with the logical thinking and research methods frequently used in DB and RM research followed by the discussion selected classical papers in the Nature “Milestone in Development”. We have also invited several outstanding DB&RM researchers to share their findings and excitement of their works. 

課程目標
1. Training in paper reading, discussion and presentation.
2. Understanding the development and frontier in DB & RM research.
3. Opportunity to interact with DB&RM researchers  
課程要求
Prerequisite courses: General Biology, Zoology, Cell Biology or Genetics. 
預期每週課後學習時數
 
Office Hours
另約時間 備註: You are welcome to make appointments with both instructors to clarify questions you may have in class.  
參考書目
Nature “Milestone in Development” (https://www.nature.com/milestones/development/milestones/index.html) 
指定閱讀
“Milestone in Development” (https://www.nature.com/milestones/development/milestones/index.html) 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
Presentation 
70% 
It will be a team presentation but graded individually. The grading will be based on the following: 1) Your understanding of the paper 2) Your presentation 3) Involement of audiance discussion  
2. 
Participation  
30% 
Send your questions asked in class or your comments or view on the subject.  
 
課程進度
週次
日期
單元主題
第1週
  Introduction 
第2週
  Research structure, logic and techniques/Fate mapping 
第3週
  Notch signaling and lateral inhibition
 
第4週
  No class
 
第5週
  Human assisted reproductive technology 
第6週
  How the fruit fly gets its stripes 
第7週
  Spemann and Mangold's organizer graft (許子易/尤子瑄) 
第9週
  Niche regulation in germ cell pluripotency and cancer
Dr. Yen-Hua Huang, Taipei Medical University 
第10週
  Nuclear reprograming and cloning (許夢恩/張慧婷)  
第11週
  Transgenics and gene knockouts (Cola Chan/劉家妤) 
第12週
  Embryonic stem cells (Howard/Crystal) 
第13週
  "Linc" Hox Gene Regulation by "Micro"managing : a Non Coding RNA Perspective
Jun-An Chen, Academia Sinica 
第14週
  Sex Chromosome (Abel/Sophie/Margo)  
第16週
  Development and Cancer (Ngoi Qi Ying/Yip Siu Ling/谢巫妙书)
 
第17週
  No Class