課程名稱 |
基因體學 Genomics |
開課學期 |
103-2 |
授課對象 |
生命科學院 生命科學所 |
授課教師 |
丁照棣 |
課號 |
LS5080 |
課程識別碼 |
B21EU2240 |
班次 |
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學分 |
3 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四@,5,6(~14:10) |
上課地點 |
生科419 |
備註 |
本課程以英語授課。必須先修習過遺傳學。 總人數上限:30人 |
Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/1032Genomics |
課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
Recent advances in genomics have significantly revolutionized the ways which we do science in the 21st century. With the completion of the human genome, the new genome technologies have transformed our ability to understand the structure and function of genomes and have enabled scientists to explore the genomes of multicellular organisms. This course is designed to introduce undergraduate students, who are interested in this exciting and rapidly evolving field, the basic knowledge of genome and the state-of-the-art genome technologies. The lectures will cover an introduction on genome projects, sequencing technologies, genetic variation, transcriptome, proteomics, functional genomics, evolutionary genomics, metagenomics and epigenomics. Additional projects will be assigned to students to full fill the course requirements. |
課程目標 |
The aim for this course is to provide students an up-to-date knowledge in genome science at the introductory level and act as a bridging course to the more advanced levels. |
課程要求 |
必須先修習過遺傳學 |
預期每週課後學習時數 |
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Office Hours |
備註: 8-10AM, Mondays |
指定閱讀 |
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參考書目 |
Introduction to Genomics by Arthur M. Lesk (2nd Edition, Oxford University Press, 2011)
A Primer of Genome Science by G. Gibson and S. V. Muse (3rd Edition, Sinauer, 2009)
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評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
Week 1 |
2/26 |
[Lecture] Introduction |
Week 2 |
3/05 |
[Homework] History of Genomics (Read the original paper)* |
Week 3 |
3/12 |
[Lecture] Genome Project
[Activity] 3-min talk: the original papers on Genomics |
Week 4 |
3/19 |
[Lecture/discussion] Sequencing Technologies |
Week 5 |
3/26 |
[Lecture] Genome Annotation
[Activity] Simple Annotation Problem Set |
Week 6 |
4/02 |
Spring Break |
Week 7 |
4/09 |
Gene Expression and Transcriptome
[Activity] Annotation project I |
Week 8 |
4/16 |
SNPs and Variation
[Activity] Annotation project II |
Week 9 |
4/23 |
Cancer Genomics
[Activity] Annotation project III |
Week 10 |
4/30 |
[Activity] Genetic testing
Homework: Annotation project IV |
Week 11 |
5/07 |
Functional Genomics
Homework: Annotation project V
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Week 12 |
5/14 |
Homework: Annotation project VI |
Week 13 |
5/21 |
Student’s presentation slides due |
Week 14 |
5/28 |
Student Presentation (15 min per slot) |
Week 15 |
6/04 |
Proteomics – protein identification, annotation and protein interactomics
Full draft of term paper due |
Week 16 |
6/11 |
Revision of term paper |
Week 17 |
6/18 |
Final version of term paper due |
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