|
Course title |
分子生物學
MOLECULAR BIOLOGY |
|
Semester |
99-1 |
|
Designated for |
COLLEGE OF LIFE SCIENCES DEPARTMENT OF BIOCHEMICAL SCIENCE AND TECHNOLOGY |
|
Instructor |
張麗冠 |
|
Curriculum Number |
BST5010 |
|
Curriculum Identity Number |
B22 U0200 |
|
Class |
|
|
Credits |
4 |
|
Full/Half
Yr. |
Half |
|
Required/
Elective |
Required |
|
Time |
Monday 3,4(10:20~12:10) Thursday 3,4(10:20~12:10) |
|
Room |
生科3A普402 |
|
Remarks |
The upper limit of the number of students: 77. |
|
Ceiba Web Server |
http://ceiba.ntu.edu.tw/991BSTMB |
|
Course introduction video |
|
|
Table of Core Capabilities and Curriculum Planning |
Table of Core Capabilities and Curriculum Planning |
|
Course Syllabus
|
|
Please respect the intellectual property rights of others and do not copy any of the course information without permission
|
|
Course Description |
分子生物學為本系必修課程之一，以往本系學生是修習生物技術中心開授之課程，與生農學院及生科系學生一起上課。由於各系學生背景分歧及教科書內容等因素，限制了授課內容並影響學生學習成效，故有必要針對本系學生開設專門課程，以奠定學生紮實的分子生物基礎
|
|
Course Objective |
藉由具系統性的課程內容及深入淺出的授課方式，使學生徹底瞭解分子生物學之重要理論及機制，並深植生技研究與應用發展的基礎。 |
|
Course Requirement |
|
|
Student Workload (expected study time outside of class per week) |
|
|
Office Hours |
|
|
Designated reading |
|
|
References |
*1. Watson, J. D., Baker, T. A., Bell, S. P., Gann, A., Levine, M. and Losick, R. (2008) Molecular Biology
of the Gene. 6th ed. Cold Spring Harbor Laboratory Press, New York.
2. Lewin, B. (2007) Genes XI. Jones & Bartlett Publishers, Inc.
3. Weaver, R. F. (2008) Molecular Biology. 4th ed. McGraw-Hill Companies, Inc.
4. Nelson, D. L. and Cox, M. M. (2008) Lehninger Principles of Biochemistry. 5th ed. W. H. Freeman
and Company, New York.
|
|
Grading |
|
|
Week |
Date |
Topic |
|
第1週 |
9/13, 9/16 |
Introduction,
Genome structure, chromatin and the nucleosome 王愛玉 |
|
第2週 |
9/20, 9/23 |
The replication of DNA (I) 王愛玉 |
|
第3週 |
9/27, 9/30 |
The replication of DNA (II) 王愛玉 |
|
第4週 |
10/4, 10/7 |
Nucleosome assembly; DNA repair (I) 王愛玉 |
|
第5週 |
10/12, 10/15 |
DNA repair (II) 王愛玉 |
|
第6週 |
10/18 |
Recombination and transposition (I) 黃楓婷 |
|
第6週 |
10/21 |
Exam 1 (王愛玉) |
|
第7週 |
10/25, 10/28 |
Recombination and transposition (I)(II) 黃楓婷 |
|
第8週 |
11/4 |
Mechanisms of transcription (I) 張麗冠 |
|
第8週 |
11/1 |
Recombination and transposition (II) 黃楓婷 |
|
第9週 |
11/8, 11/11 |
Mechanisms of transcription (II); RNA splicing (I) 張麗冠 |
|
第10週 |
11/15, 11/18 |
RNA splicing (II) 張麗冠 |
|
第11週 |
11/22, 11/25 |
Translation (I) 張麗冠 |
|
第12週 |
11/29, 12/2 |
Translation (II) 張麗冠 |
|
第13週 |
12/6 |
Transcriptional regulation in prokaryotes 張麗冠 |
|
第14週 |
12/9 |
Exam 2 (黃楓婷; 張麗冠 ) |
|
第14週 |
12/13, 12/16 |
Transcriptional regulatory in eukaryotes (I) 張麗冠 |
|
第15週 |
12/20, 12/23 |
Transcriptional regulatory in eukaryotes (II) 張麗冠 |
|
第16週 |
12/27, 12/30 |
Regulatory RNAs 王愛玉 |
|
第17週 |
1/3, 1/6 |
Genome analysis and systems biology;
Techniques of molecular biology
廖憶純 |
|
第18週 |
1/13 |
Exam 3 (張麗冠;王愛玉;廖憶純) |
|