課程名稱 |
族群遺傳學 Population Genetics |
開課學期 |
113-1 |
授課對象 |
生命科學院 基因體與系統生物學學位學程 |
授課教師 |
王弘毅 |
課號 |
EEB5045 |
課程識別碼 |
B44EU1570 |
班次 |
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學分 |
3.0 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
星期四2,3,4(9:10~12:10) |
上課地點 |
生科419 |
備註 |
本課程以英語授課。最好修過遺傳學或演化生物學。教室:生科419。與丁照棣、李承叡合授 總人數上限:40人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
The course is designed for students who are interested in genetics, genomics, and evolution. It will introduce theories of population genetics and explain molecular data in the context of population genetics. The course also discuss how genetic diversity is generated and estimated.
Webex Link: https://ntucc.webex.com/ntucc-en/j.php?MTID=mcfaa6b91f66f14678d295b9763e2f81b |
課程目標 |
The course aims to introduce basic theory of population genetics and how molecular data are interpreted within this framework. |
課程要求 |
It is recommended that students taking this course should have basic concepts of algebra and calculus. |
預期每週課後學習時數 |
3-4 hours |
Office Hours |
每週四 12:00~12:50 |
指定閱讀 |
Population genetics by Matthew B. Hamilton (Wiley-Blackwell 2021) |
參考書目 |
A Primer of Population Genetics and Genomics by Daniel L. Hartl (Oxford 2020)
Population Genetics and Microevolutionary Theory by Alan R. Templeton (Wiley 2021)
Population Genetics with R: An Introduction for Life Scientists by Aki Jarl Laruson and Floyd Allan Reed (Oxford 2021) |
評量方式 (僅供參考) |
No. |
項目 |
百分比 |
說明 |
1. |
Homework |
40% |
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2. |
midterm |
30% |
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3. |
Final Examination |
30% |
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針對學生困難提供學生調整方式 |
上課形式 |
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作業繳交方式 |
學生與授課老師協議改以其他形式呈現 |
考試形式 |
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其他 |
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週次 |
日期 |
單元主題 |
第1週 |
9/5 |
Introduction/ Thinking like a population geneticist (Ting) |
第2週 |
9/12 |
Genetic Polymorphisms
Organization of Genetic Variation (Ting)
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第3週 |
9/19 |
Genotype frequencies (Ting) |
第4週 |
9/26 |
Genetic drift and effective population size (Ting) |
第5週 |
10/3 |
Invited speaker: Coalescent theory (10:00-12:00) |
第6週 |
10/10 |
Holiday (No lecture) |
第7週 |
10/17 |
Population structure and gene flow (Lee) |
第8週 |
10/24 |
Mutation (Lee) |
第9週 |
10/31 |
Midterm (Lee) |
第10週 |
11/7 |
Quantitative trait variation and evolution (Lee) |
第11週 |
11/14 |
The Mendelian basis of quantitative trait variation (Lee) |
第12週 |
11/21 |
Fundamentals of natural selection (Wang) |
第13週 |
11/28 |
Fundamentals of natural selection (Wang) |
第14週 |
12/5 |
Molecular evolution (Wang) |
第15週 |
12/12 |
Human evolution (Wang) |
第16週 |
12/19 |
Final exam (Wang) |