課程資訊
課程名稱
真核生物多樣性與演化
Diversity and Evolution of Eukaryotes 
開課學期
113-1 
授課對象
生命科學院  生命科學院院學士學位  
授課教師
顧 銓 
課號
EEB5095 
課程識別碼
B44EU2070 
班次
 
學分
2.0 
全/半年
半年 
必/選修
選修 
上課時間
星期五5,6(12:20~14:10) 
上課地點
共202 
備註
本課程以英語授課。需先修過普通生物學或相當課程。
總人數上限:24人 
 
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課程概述

This is an introductory course on the diversity of eukaryotes in different aspects — from genomes to ecological interactions. Major topics include evolutionary relationships and history, cell structures and functions, and importance for various ecosystems and humanity. The emphasis is on eukaryotes that are not land plants, animals, or fungi — namely protists (algae and non-photosynthetic microbial eukaryotes, including diverse amebae, flagellates and shelled microbes). 

課程目標
The student will acquire a basic understanding of:
1. Evolutionary origin and history of eukaryotes and their organelles
2. Diversity of eukaryotic genomes, cells, and organismic biology
3. Major eukaryotic lineages and important eukaryotic microbes
4. Relationships between eukaryotic microbes and Earth, ecosystems, humans, and other organisms 
課程要求
General Biology or equivalent courses
Genomics, Cell Biology, Evolutionary Biology, and Ecology are relevant, but not required. 
預期每週課前或/與課後學習時數
2 hr 
Office Hours
另約時間 備註: Instructor: Chuan Ku (chuanku@ntu.edu.tw) Course TA: Ming-Wei Lai (mwlai@gate.sinica.edu.tw) 
指定閱讀
Course slides (midterm and final exam)

Additional reading (extra points for final exam):
Sun et al., Host range and coding potential of eukaryotic giant viruses. Viruses 12, 1337 (2020).
Wells et al., Algae as nutritional and functional food sources: revisiting our understanding. J. Appl. Phycol. 29:949–82 (2017). 
參考書目
1. Archibald et al., Eds., Handbook of the Protists (Springer, ed. 2nd, 2017). 2. Adl et al., Revisions to the classification, nomenclature, and diversity of eukaryotes. J. Eukaryot. Microbiol. 66, 4–119 (2019). 3. Lee, Phycology (Cambridge University Press, Cambridge, ed. 4, 2008). 4. Willey et al., Prescott’s Microbiology (McGraw-Hill Education, ed. 10, 2017). 5. Alberts et al., Molecular Biology of the Cell (Garland Science, ed. 6, 2015). 6. Other selected review articles and research papers. 7. Adl, Protistology (Elsevier, ed. 1, 2024)
Selected review articles and research papers 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
Mid-term exam 
25% 
Materials from weeks 1-7 
2. 
Final exam 
25% 
Materials from weeks 9-13 (incl. concepts from weeks 1-7) and two assigned papers 
3. 
Oral 
15% 
 
4. 
Written 
15% 
 
5. 
Attendence 
10% 
 
6. 
In class 
10% 
 
 
課程進度
週次
日期
單元主題
第1週
September 6, 2024   Introduction 
第2週
September 13, 2024   Origin and early evolution of eukaryotes
 
第3週
September 20, 2024   Evolution of endosymbiotic organelles 
第4週
September 27, 2024   Cellular structures 
第5週
October 4, 2024   Metabolism, nutrition and cellular interactions 
第6週
October 11, 2024   Lab Demonstration:
Flow cytometry, cell sorting, and microscopy for microbial eukaryotes
(Venue: R220 and R106 at Institute of Plant and Microbial Biology, Academia Sinica) 
第7週
October 18, 2024   Cell cycle and life cycle 
第8週
October 25, 2024   Midterm exam 
第9週
November 1, 2024   Card Game:
Survival of microbes 
第10週
November 8, 2024   Amorphea (Opisthokonts and Amoebozoans)  
第11週
November 15, 2024   Archaeplastids
SAR: Stramenopiles, Alveolates, Rhizarians 
第12週
November 22, 2024   Haptists, Cryptists, Discobans and other eukaryotes 
第13週
November 29, 2024   Protists, Earth and humans 
第14週
December 6, 2024   Student oral presentations 
第15週
December 13, 2024   Written assignment due
Course wrap up 
第16週
December 20, 2024   Final exam