課程資訊
課程名稱
癌症分子生物學
MOLECULAR BIOLOGY OF THE CANCER 
開課學期
97-2 
授課對象
生命科學院  生化科學研究所  
授課教師
陳宏文 
課號
BChem7020 
課程識別碼
B46 M1250 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期四2,3,4(9:10~12:10) 
上課地點
生化N101 
備註
與李明亭、張茂山合開
總人數上限:50人 
 
課程簡介影片
 
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課程概述

Cancer biology is a relatively new area of biology. The development of new concepts in cancer biology will be lectured by introduction of oncogenes, tumor suppressor genes, metastasis, and cancer therapy at the molecular and cellular level.  

課程目標
The goal of this class is to provide students an overview of the development of contemporary cancer biology and new concepts in the field. The class is also intended to provide a foundation to students who are interested in cancer research. 
課程要求
(1) The lectures are primarily intended for graduate students.
(2) Electronic files of teaching materials will be available in advance of each class.
(3) Mid-term and final exams are in the format of in-class written test.
(4) Only the materials from lectures will be used for the exams. However, students are urged to go through the textbook too.
 
預期每週課後學習時數
 
Office Hours
: ~ : 備註: 與李明亭,張茂山合開 
參考書目
“The Biology of Cancer” by Robert A. Weinberg (2007) 
指定閱讀
 
評量方式
(僅供參考)
 
No.
項目
百分比
說明
1. 
期中考 
50% 
 
2. 
期末考 
50% 
 
 
課程進度
週次
日期
單元主題
第1週
2/19  Chapter 2 (The Nature of Cancer) 
第2週
2/26  Chapters 3 & 4 (Tumor Viruses; Cellular Oncogenes) 
第3週
3/05  Chapter 5 (Growth Factors and Their Receptors) 
第4週
3/12  Chapter 6 (Cytoplasmic Signaling Circuitry Programs Many of the Traits of Cancer) 
第5週
3/19  Chapter 7 (Tumor Suppressor Genes)
 
第6週
3/26  Chapter 8 (pRB and control of Cell Cycle) 
第7週
4/02  Chapter 9 (p53 and Apoptosis: Master Guardian and Executioner) 
第8週
4/09  Mid-term Examination 
第9週
4/16  Chapters 10 & 11 (Eternal Life & Tumorigenesis) 
第10週
4/23  Chapter 12 (Maintenance of Genomic Integrity) 
第11週
4/30  Chapter 13 (Dialogue Replaces Monologue: Heterotypic Interactions and the Biology of Angiogenesis) 
第12週
5/07  Chapter 14 (Moving Out: Invasion and Metastasis) 
第13週
5/14  Chapter 15 (Crowd Control: Tumor Immunology & Immunotherapy) 
第14週
5/21  Chapter 15 (Crowd Control: Tumor Immunology
& Immunotherapy) 
第15週
5/28  端午節 
第16週
6/04  Chapter 16 (Treatment of Cancer) 
第17週
6/11  General Discussion 
第18週
6/18  Final Examination