課程資訊
課程名稱
碩士班專題討論
SEMINAR (M.S) 
開課學期
113-1 
授課對象
生命科學院  基因體與系統生物學學位學程  
授課教師
朱雪萍 
課號
GenSys7003 
課程識別碼
B48EM0220 
班次
 
學分
1.0 
全/半年
半年 
必/選修
必修 
上課時間
星期四6,7(13:20~15:10) 
上課地點
 
備註
本課程以英語授課。碩/博士班專題討論合班授課,上課地點生科館4C/中研院。與陳律佑、潘思樺、林友瑜、吳亭穎合授
總人數上限:15人 
 
課程簡介影片
 
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課程概述

Style:Journal report

(1) Please choose three papers from the last two years that are related to systems biology and send them to the teaching assistants two weeks before the report. Students must send the TA the candidate papers at least 2 weeks before the presentation, but the earlier the better. The teaching assistants will ask the teachers to vote on the report themes and then notify the students of the topics that can be reported.
Presentation time is within 60 minutes for a student (45 minutes of presentation, 15 minutes of questions). The other students (audience) need to fill out the feedback and score sheet, as shown in the appendix. This course is a journal club in English. When preparing your report, please consider students and teachers from different backgrounds.

(2) Grading rules:
2.1. Speech performance: including slide contents, oral expression, time control, questions and answers, and presentation style
2.2. The final grade is the sum of the student's average grade (40%), and the teacher's average grade (60%). Scores should be in the 70-95 range as much as acceptable. If the score is higher than 95 or lower than 70, the reasons must be explained.
2.3. Bonus: Attendance rate, score sheets, and the frequency of asking questions as the bonus points (For the bonus part, the total number of questions asked is 1 point for more than 5 times and 2 points for more than 10 times; full attendance and no missed submissions add up to 2 points.) 

課程目標
待補 
課程要求
 
預期每週課前或/與課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
 
評量方式
(僅供參考)
 
  1. 本校尚無訂定 A+ 比例上限。
  2. 本校採用等第制評定成績,學生成績評量辦法中的百分制分數區間與單科成績對照表僅供參考,授課教師可依等第定義調整分數區間。詳見學習評量專區 (連結)。
 
課程進度
週次
日期
單元主題
Week 1
9/5  Introduction (Online)
Google meet:
meet.google.com/pyp-xddh-qjv 
Week 2
9/12  No class 
Week 3
9/19  No class 
Week 4
9/26  No class 
Week 5
10/3  No class 
Week 6
10/10  (National Day) 
Week 7
10/17  謝雨彤 (YU-TUNG HSIEH) (@NTU LS 4C)
DNA damage signaling in Drosophila macrophages modulates systemic cytokine levels in response to oxidative stress (eLife 2023)
https://elifesciences.org/reviewed-preprints/86700v2#tab-content 
Week 8
10/24  陳哲緯 (CHEN, JE WEI) (@NTU LS 4C)
GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies. (Molecular cell 2024)
https://www.sciencedirect.com/science/article/pii/S1097276524002843?via%3Dihub#cebib0010 
Week 9
10/31  許舒瑜 (SHU-YU HSU) (@NTU LS 4C)
Mechanisms of readthrough mitigation reveal principles of GCN1-mediated translational quality control (Cell 2023)
https://www.cell.com/cell/fulltext/S0092-8674(23)00587-1 _returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867423005871%3Fshowall%3Dtrue 
Week 10
11/7  張荷清 (HO-CHING CHANG) (@NTU LS 4C)
Large-scale deep multi-layer analysis of Alzheimer’s disease brain reveals strong proteomic disease-related changes not observed at the RNA level. (Nat Neurosci 2022)
https://www.nature.com/articles/s41593-021-00999-y 
Week 11
11/14  NGUYEN VUONG THAO VY (@NTU LS 4C)
Single-cell RNA-seq uncovers dynamic processes orchestrated by RNA-binding protein DDX43 in chromatin remodeling during spermiogenesis. (Nature Communications 2023)
https://www.nature.com/articles/s41467-023-38199-w?fromPaywallRec=false 
Week 12
11/21  何彥禛 (YANN-JEN HO) (@Sinica IMB N401)
Rodríguez-Temporal, D., Herrera, L., Alcaide, F., Domingo, D., Héry-Arnaud, G., van Ingen, J., ... & Rodríguez-Sánchez, B. (2023). Identification of Mycobacterium abscessus subspecies by MALDI-TOF mass spectrometry and machine learning. Journal of clinical microbiology, 61(1), e01110-22.
https://pubmed.ncbi.nlm.nih.gov/36602341/ 
Week 13
11/28  孫國瑞 (SUN, KUO-JUI) (@Sinica IMB N401)
Platelets regulate ischemia-induced revascularization and angiogenesis by secretion of growth factor–modulating factors
https://ashpublications.org/bloodadvances/article/7/21/6411/496124/Platelets-regulate-ischemia-induced 
Week 14
12/5  胡昱庭 (YU-TING, HU)(@Sinica IMB N401)
Dynamic behaviour restructuring mediates dopamine-dependent credit assignment
https://www.nature.com/articles/s41586-023-06941-5 
Week 15
12/12  葉政翔 (ZHENG-XIANG YE) (@Sinica IMB N401)
Gene trajectory inference for single-cell data by optimal transport metrics
https://www.nature.com/articles/s41587-024-02186-3 
Week 16
12/19  THI NGAN GIANG NGUYEN(@Sinica IMB N401)
Adipose tissue retains an epigenetic memory of obesity after weight loss
https://www.nature.com/articles/s41586-024-08165-7