課程名稱 |
神經發育與疾病 Neural Development and Disease |
開課學期 |
110-2 |
授課對象 |
生命科學院 跨領域神經科學國際研究生博士學位學程 |
授課教師 |
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課號 |
TIPGIN8011 |
課程識別碼 |
B49 D0300 |
班次 |
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學分 |
3.0 |
全/半年 |
半年 |
必/選修 |
選修 |
上課時間 |
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上課地點 |
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備註 |
總人數上限:30人 |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
課程大綱
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課程概述 |
此課程主題包括神經發育的基本概念,有Neural induction, neuronal fate specification, neurite fate determination, dendrite development, axon guidance, synapse development 以及 circuit formation. 另外此課程也以特別講座的形式介紹 molecular and cellular aspects of neuroscience, neuron-glia interaction 和神經系統的疾病。 |
課程目標 |
在發育過程中產生健全的神經系統是我們能認知, 學習及進行各項活動的基礎 因此研究神經發育為相當重要的課題 |
課程要求 |
有修過分子生物學與細胞生物學的同學較適合修本課程 |
預期每週課後學習時數 |
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Office Hours |
備註: Class Time: 13:30-16:30, Wednesday
Room: C101, Interdisciplinary Building, Academia Sinica |
指定閱讀 |
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參考書目 |
Development of the Nervous System (3rd) by Dan H. Sanes et al. |
評量方式 (僅供參考) |
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週次 |
日期 |
單元主題 |
Week 1 |
2020/3/4 |
Embryonic polarity and Induction, Dr. Jun-An Chen陳俊安 |
Week 2 |
2020/3/11 |
Fate specification and patterning, Dr. Shen-Ju Chou周申如 |
Week 3 |
2020/3/18 |
Determination of neurite fate, Dr. Pei-Lin Cheng鄭珮琳 |
Week 4 |
2020/3/25 |
Axon guidance, target selection and connection, Dr. Yung Shu Kuan 管永恕 |
Week 5 |
2020/4/1 |
Dendrite development, Dr. Cheng-Ting Chien 簡正鼎 |
Week 6 |
2020/4/8 |
Pre-synapse formation and function, Dr. Chi-Kuang Yao姚季光 |
Week 7 |
2020/4/15 |
Post-synapse formation, Dr. Shu-Ling Chiu 丘淑鈴 |
Week 8 |
2020/4/22 |
Ion channels in nervous system, Dr. Shi-Bing Yang 楊世斌 |
Week 9 |
2020/4/29 |
Neural circuits and behavior, Dr. Sue-Wei Lin林書葦 |
Week 10 |
2020/5/6 |
RNA biology in neural development and diseases, Dr. Guey-Shin Wang 王桂馨 & Dr. Woan-Yuh Tarn 譚婉玉 |
Week 11 |
2020/5/13 |
Midterm (development part—to circuit formation) |
Week 12 |
2020/5/20 |
Glia development, Dr. Henry Sun 孫以瀚 |
Week 13 |
2020/5/27 |
Glia in Huntinton’s disease, Dr. Yijuang Chern 陳儀莊 |
Week 14 |
2020/6/3 |
Centrosomes in brain development and disease, Dr. Tang K. Tang唐堂 |
Week 15 |
2020/6/10 |
Alzheimer’s disease (circuit spreading mechanism), Dr. Yung-Feng Liao廖永豐 |
Week 16 |
2020/6/17 |
Final exams (disease part), close-book style |
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