This course offers an introduction to basic and advanced biotechnology systems with an emphasis on the use of transgenic approaches for research in modern biosciences. The lectures include approaches using genomics, epigenetics, proteomics, and metabolomics to study key questions for biotechnology development. Examples comprise plant and animal disease models and their interactions with microbes to deliver valuable biological molecules and agricultural products. Students taking this course are required to submit two term papers aiming the training for writing a research proposal on biotechnology to address key questions in cutting-edge biotechnology and an invention disclosure to pursue patent protection based on recent progress in biological science.